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LIFE Forschungszentrum

Publikationen 2013

Amemiya CT, … Hoffmann S,…. Stadler PF,…..et al.
The African coelacanth genome provides insights into tetrapod evolution. Nature 496(7445) DOI: 10.1038/nature12027

Benz C, Retzbach H, Belder D.
Protein–protein interaction analysis in single microfluidic droplets using FRET and fluorescence lifetime detection. Lab Chip 13(14) DOI: 10.1039/C3LC00057E

Binder H, Steiner L, Przybilla J, Rohlf T, Prohaska S, Galle J.
Transcriptional regulation by histone modifications: towards a theory of chromatin re-organization during stem cell differentiation. Phys Biol 10(2) doi: 10.1088/1478-3975/10/2/026006

Breitfeld J, Heiker JT, Böttcher Y, Schleinitz D, Tönjes A, Weidle K, Krause K, Kuettner EB, Scholz M, Kiess W, Sträter N, Beck-Sickinger AG, Stumvoll M, Körner A, Blüher M, Kovacs P. 
Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels. J Mol Med 91(11) DOI: 10.1007/s00109-013-1062-9

Breitfeld J, Tönjes A, Gast MT, Schleinitz D, Blüher M, Stumvoll M, Kovacs P, Böttcher Y, Role of vaspin in human eating behaviour,  Plos One 2013, DOI: 10.1371/jounal.pone.0054140

Ceglarek U., Dittrich J, Becker S, Baumann F, Kortz L, Thiery J.
Quantification of seven apolipoproteins in human plasma by proteotypic peptides using fast LC-MS/MS. Proteomics Clin 7 DOI: 10.1002/prca.201300034

Christensen MK, Erichsen KD, Olesen UH, Tjornelund J, Fristrup P, Thougaard A, Nielsen SJ, Sehested M, Jensen PB, Loza E, Kalvinsh I, Garten A, Kiess W, Björkling F, Nicotinamide Phosphoribosyltransferase Inhibitors, Design, Preparation, and Structure–Activity Relationship, J Medical Chemistry , 2013, DOI: 10.1021/jm4009949

Dieterich C, Stadler PF, Computational biology of RNA interactions, Wiley Interdiscip Rev RNA, 2013, DOI: 10.1002/wrna.1147

Doose G, Alexis M, Kirsch R, Findeiß S, Langenberger D, Machné R, Mörl M, Hoffmann S, Stadler PF.
Mapping the RNA-Seq trash bin: Unusual transcripts in prokaryotic transcriptome sequencing data. RNA Biol. 10(7) DOI: 10.4161/rna.24972

Dukart J, Kherif F, Mueller K, Adaszewski S, Schroeter ML, Frackowiak RS, Draganski B.
Generative FDG-PET and MRI model of aging and disease progression in Alzheimer's disease. PLoS Comput Biol 9(4) DOI: 10.1371/journal.pcbi.1002987

Dukart J, Mueller K, Villringer A, Kherif F, Draganski B, Frackowiak R, Schroeter ML.
Relationship between imaging biomarkers, age, progression and symptom severity in Alzheimer's disease. Neuroimage Clin 3 DOI: 10.1016/j.nicl.2013.07.005

Dukart J, Perneczky R, Förster S, Barthel H, Diehl-Schmid J, Draganski B, Obrig H, Santarnecchi E, Drzezga A, Fellgiebel A, Frackowiak R, Kurz A, Müller K, Sabri O, Schroeter ML, Yakushev I.
Reference Cluster Normalization Improves Detection of Frontotemporal Lobar Degeneration by Means of FDG-PET. PlosONE 8(2) DOI: 10.1371/journal.pone.0055415

Dukart J, Mueller K, Barthel H, Villringer A, Sabri O, Schroeter L, and the Alzheimer's Disease Neuroimaging Initiative
Meta-analysis-based SVM classification enables accurate detection of Alzheimer's disease accros different clinical centers using  FDG-PET and MRI. Psychiat Res-Neuroim 212(3) DOI: 10.1016/j.pscychresns.2012.04.007

Fasold M, Binder H
AffyRNADegradation: Control and correction of RNA quality effects in GeneChip expression data. Bioinformatics 29(1) DOI: 10.1093/bioinformatics/bts629

Frisch S, Dukart J, Vogt B, Horstmann A, Becker G, Villringer A, Barthel H, Sabri O, Müller K, Schroeter ML.
Dissociating Memory Networks in Early Alzheimer’s Disease and Frontotemporal Lobar egeneration – A Combined Study of Hypometabolism and Atrophy. PlosONE 8(2) DOI: 10.1371/journal.pone.0055251

Gast MT, Tönjes A, Keller M, Horstmann A, Steinle N, Scholz M, Müller I, Villringer A, Stumvoll M, Kovacs P, Böttcher Y. 
The role of rs2237781 within GRM8 in eating behavior. Brain and Behavior 3(5) DOI:  10.1002/brb3.151

Hasenclever D, Scholz M.
Comparing measures of association in 2x2 probability tables. arXiv 1302.6161 (math. ST)

Hass J, Walton E, Kirsten H, Liu J, Priebe L, Wolf C, Karbalai N, Gollub R, White T, Roessner V, Müller KU, Paus T, Smolka MN, Schumann G; IMAGEN Consortium, Scholz M, Cichon S, Calhoun V, Ehrlich S.
A Genome-Wide Association Study Suggests Novel Loci Associated with a Schizophrenia-Related Brain-Based Phenotype. PlosONE 8(6) DOI: 10.1371/journal.pone.0064872

Helmschrodt C, Becker S, Schröter J, Hecht M, Aust G, Thiery J, Ceglarek U.
Associated with a Schizophrenia-Related Brain-Based. Clin Chim Acta. 425 DOI: 10.1016/j.cca.2013.06.022

Holdt LM, von Delft A, Nicolaou A, Baumann S, Kostrzewa M, Thiery T, Teupser D. 
Quantitative Trait Loci Mapping of the Mouse Plasma Proteome (pQTL). Genetics 193 DOI: 10.1534/genetics.112.143354

Holdt ML, Hoffmann S, Sass K, Langenberger D, Scholz M, Krohn K, Finstermeier K, Stahringer A, Wilfert W, Beutner F, Gielen S, Schuler G, Gäbel G, Bergert H, Bechmann I, Stadler PF, Thiery J, Teupser D
Phenotype. Plos Genetics 9(7) DOI: 10.1371/journal.pgen.1003588

Holiga Š, Mueller K, Möller HE, Sieger T, Schroeter ML, Vymazal J, Růžička E, Jech R. 
Motor matters: tackling heterogeneity of Parkinson's disease in functional MRI studies. PlosONE 8(2) DOI: 10.1371/journal.pone.0056133

Holland H, Xu LX, Ahnert P, Kirsten H, Koschny R, Bauer M, Schober R, Meixensberger J, Krupp W. 
Comprehensive high-resolution genomic profiling and cytogenetics of two pediatric and one adult medulloblastoma. Pathol Res Pract 209(9) DOI: 10.1016/j.prp.2013.06.001

Holmes MV, ... Holdt LM, Beutner F, ... Teupser D, ... et al. 
Secretory Phospholipase A2-IIA and Cardiovascular Disease: a Mendelian randomization study. J Am Coll Cardiol. 62(21) DOI: 10.1016/j.jacc.2013.06.044

Hopp L, Lembcke K, Binder H, Wirth H.
Portraying the Expression Landscapes of B-Cell Lymphoma-Intuitive Detection of Outlier Samples and of Molecular Subtypes. Biology 2(4) DOI: 10.3390/biology2041411

Hopp L, Wirth H, Fasold M, Binder H.
Portraying the expression landscapes of cancer subtypes: A case study of glioblastoma multiforme and prostate cancer case. Systems Biomedicine 1(2) DOI: 10.4161/sysb.25897

Horikoshi M,..., Kiess W, ...; Early Growth Genetics (EGG) Consortium, New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism., NatGenetics, 2013, DOI:10.1038/ng.2477

Jech R, Mueller K, Schroeter ML, Ruzicka E.
Levodopa increases functional connectivity in the cerebellum and brainstem in Parkinson’s disease. Brain 136(7) doi: 10.1093/brain/awt015

Keller M, Schleinitz D, Müller I, Stumvoll M, Kovacs P, Blüher M, Böttcher Y.
Global methylation level in human adipose tissue is related to fat distribution. Diabetologie und Stoffwechsel, Kongressbeitrag 8 DOI: 10.1055/s-0033-1341831

Kortz L, Dorow J, Becker S, Thiery J, Ceglarek U.
Fast liquid chromatography–quadrupole linear ion trap-mass spectrometry analysis of polyunsaturated fatty acids and eicosanoids in human plasma. J Chromatogr B 927 DOI: 10.1016/j.jchromb.2013.03.012

Kralisch S, Tönjes A, Krause K, Richter J, Lossner U, Kovacs P, Ebert T, Blüher M, Stumvoll M, Fasshauer M, Fibroblast growth factor-21 serum concentrations are associated with metabolic and hepatic markers in humans, J Endocrinology 2013, DOI: 10.1530/JOE-12-0367

Krinner A, Roeder I, Loeffler M, Scholz M.
Merging concepts - coupling an agent-based model of hematopoietic stem cells with an ODE model of granulopoiesis. BMC Syst Biol 7(1) Doi: 10.1186/1752-0509-7-11

Küntzelmann A, Guenther t, Haberkorn U, Essig M, Giesel F, Henze R, Schroeter ML, Schröder J, Schönknecht P, Impaired cerebral glucose metabolism  in prodromal Alzheimer’s disease differs by regional intensity normalization, J Neuroscience Letters, 2013, DOI: 10.1016/j.neurolet.2012.11.026

Langenberger D, Çakir MV, Hoffmann S, Stadler PF.
Dicerprocessed small RNAs: Rules and exceptions. J. Exp. Zool. (Mol. Dev. Evol.) 320B DOI: 10.1002/jez.b.22481

Larsen PS, …, Kiess W, ... et al.
Pregnancy and Birth Cohort Resources in Europe: a Large Opportunity for Aetiological Child Health Research. Paediatr Perinat Epidemiol. 27 DOI: 10.1111/ppe.12060

Li Y, Podlevsky JD, Marz M, Qi X, Hoffmann S, Stadler PF, Chen JJ.
Identification of purple sea urchin telomerase RNA using a next-generation sequencing based approach. RNA 19(6) DOI: 10.1261/rna.039131.113

Luck T, Motzek T, Luppa M, Matschinger H, Fleischer S, Sesselmann Y, Roling G, Beutner K, König HH, Behrens J, Riedel-Heller SG. 
Effectiveness of preventive home visits in reducing the risk of falls in old age: a randomized controlled trial. Clin Interv Aging. 8 DOI: 10.2147/CIA.S43284

Luppa M, Luck T, Ritschel F, Angermeyer MC, Villringer A, Riedel-Heller SG. 
Depression and incident dementia. An 8-year population-based prospective study. PlosONE 8(3) DOI: 10.1371/journal.pone.0059246

Miersch A, Vogel M, Gausche R, Siekmeyer W, Pfäffle R, Dittrich K, Kiess W. Blood pressure tracking in children and adolescents. Pediatr Nephrol 2013, DOI:10.1007/s00467-013-2596-3

Miersch A, Vogel M, Gausche R, Siekmeyer W, Pfäffle R, Dittrich K, Kiess W. Influence of seasonal variation on blood pressure measurements in children, adolescents and young adults. Pediatr Nephrol, 2013, DOI: 10.1007/s00467-013-2562-0

Mueller K, Jech R, Schroeter ML.
Deep-Brain Stimulation for Parkinson's Disease. New Engl J Med 368 (5) DOI: 10.1056/NEJMc1214078

Neef M, Weise S, Adler M, Sergeyev E, Dittrich K, Körner A, Kiess W. Health impact in children and adolescents, j Clinical Endocrinology, 2013, DOI: org/10.1016/jbeem.2013.02.007

Nitsche A, Doose G, Tafer H, Robinson M, Saha NR, Gerdol M, Canapa A, Hoffmann S, Amemiya CT, Stadler PF.
Atypical RNAs in the coelacanth transcriptome. J. Exp. Zool. (Mol. Dev. Evol.) 9999B DOI: 10.1002/jez.b.22542

Olbrich S, Olbrich H, Adamaszek M, Jahn I, Hegerl U, Stengler K. Altered EEG lagged coherence during rest in obsessive-compulsive disorder. Clinical Neurophys. 124, 2421-2430, DOI: org/10.1016/j.clinph.2013.05.031

Pierzchalski A, Mittag A, Bocsi J, Tarnok A.
An Innovative Cascade System for Simultaneous Separation of Multiple Cell Types. PlosONE 8(9) DOI: 10.1371/journal.pone.0074745

Raschpichler M, Kees S, Schroeter ML, Arelin K, Schlögl H, Fritzsch D, Mende M, Pampel A, Böttcher Y, Stumvoll M, Villringer A, Müller K.
Abdominal fat distribution and its relationship to brain changes - the differential effects of age on cerebellar structure and function. BMJopen 3(1) Doi: 10.1136/bmjopen-2012-001915

Reiprich M, Rudzok S, Schütze N, Simon JC, Lehmann I, Trump S, Polte T.
Inhibition of endotoxin-induced perinatal asthma protection by pollutants in an experimental mouse model. AllergyInhibition of endotoxin-induced perinatal asthma protection by pollutants in an experimental mouse model. Allergy 68(4) DOI:  10.1111/all.12121 

Scheibe, P, Lazareva A, Braumann UD, Reichenbach A, Wiedemann P, Francke M, Rauscher FG.
Parametric Model for the 3D Reconstruction of Individual Fovea Shape from OCT Data. Experimental Eye Research 119 DOI: 10.1016/j.exer.2013.11.008.

Schirm S, Engel C, Loeffler M, Scholz M.
A Biomathematical Model of Human Erythropoiesis under Erythropoietin and Chemotherapy Administration. PLoS ONE 8(6) DOI: 10.1371/journal.pone.0065630

Schroeter ML, Sacher J, Steiner J, Schoenknecht P, Mueller K.
Serum S100B Represents a New Biomarker for Mood Disorders. Curr Drug Targets 14(11) DOI: 10.2174/13894501113149990014

Sergeyev  E, Wagner I, Neef M, Adler M, Körner A, Kiess W. Störungen des Kohlenhydratstoffwechsels bei Kindern und Jugendlichen mit Adipositas, Bundesgesungheitsbl 2013, DOI: 10.1007/s00103-012-1636-7

Spinnler R, Gorski T, Stolz K, Schuster S, Garten A, Beck-Sickinger AG, Engelse MA, de Koning EJ, Körner A, Kiess W, Maedler K.
The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion. PlosONE 8(1) DOI: 10.1371/journal.pone.0054106

Stadler SC, Vincent CT, Fedorov VD, Patsialou A, Cherrington BD, Wakshlag JJ, Mohanan S, Zee BM, Zhang X, Garcia BA, Condeelis JS, Brown AM, Coonrod SA, Allis CD. 
Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells. PNAS 110(29) DOI: 10.1073/pnas.1308362110

Teren A, Beutner F, Wirkner K, Loeffler M, Scholz M.
Validity, intra- and inter-observer reliability of automated devices for the assessment of ankle brachial index using photo-plethysmography. BMC Cardiovasc Disord 13(1) DOI: 10.1186/1471-2261-13-81

Then FS, Luck T, Jacobi F, Berger K, Weyerer S, Grabe HJ, Busch MA, Wagner M, Riedel-Heller SG. 
Assessment of mild cognitive impairment and dementia in epidemiologic studies. An overview on the current state of research in Germany. Psychiatr Prax. 40(4) DOI: 10.1055/s-0033-1343138

Then FS, Luppa M, Schroeter ML, König HH, Angermeyer MC, Riedel-Heller SG. 
Enriched environment at work and the incidence of dementia: results of the Leipzig longitudinal study of the aged (LEILA 75+). PlosONE 8(7) DOI: 10.1371/journal.pone.0070906

Thomas S, Kratzsch D, Schaab M, Scholz M, Grunewald S, Thiery J, Paasch U, Kratzsch J.
Seminal plasma adipokine levels are correlated with functional characteristics of spermatozoa. Fertil Steril 99(5) DOI: 10.1016/j.fertnstert.2012.12.022

Tomm JM, van Do T, Jende C, Simon JC, Treudler R, von Bergen M, Averbeck M.
Identification of new potential allergens from Nile perch (Lates niloticus) and cod (Gadus morhua). JIACJ 23(3) 

Treudler R, Simon JC.
Allergierisiko durch zunehmende Ausbreitung der Ambrosiapflanze. Ärzteblatt Sachsen 10/2013

Wallborn T, Grafe N, Quante M, Geserick M, Casprzig N, Ludwig J, Hiemisch A, Kiess W.
Never plan a population based cohort study on a rainy Friday after a sunny Thursday. Eur J Epidemiol 28(3) DOI: 10.1007/s10654-013-9774-2

Woost TB, Dukart J, Frisch S, Barthel H, Sabri O, Mueller K, Schroeter ML. 
Neural correlates of the DemTect in Alzheimer's disease and frontotemporal lobar degeneration - A combined MRI & FDG-PET study. Neuroimage Clin 2 DOI: 10.1016/j.nicl.2013.05.008

Xiaodong Q, Yang L, Honda S, Hoffmann S, Marz M, Mosig A, Podlevsky JD, Stadler PF, Selker EU, Chen JJL, The common ancestral core of vertebrate and fungal telomerase RNAs, Nucleic Acids Research, 2013, DOI: 10.1093/nar/gks980

Yang L, Podlevsky JD, Marz M, Qi X, Hoffmann S, Stadler PF, Chen JJL,  Identification of purple sea urchin telomerase RNA using a next-generation sequencing based approach, RNA Journal 2013, DOI: 10.1261/rna.039131.113

Zeynalova S, Ziepert M, Scholz M, Schirm S, Zwick C, Pfreundschuh M, Loeffler M; German High-Grade Non-Hodgkin Lymphoma Study Group (DSHNHL).
Comparison and modelling of pegylated or unpegylated G-CSF schedules in CHOP-14 regimen of elderly patients with aggressive B-cell lymphoma. Ann Hematol 92(12) DOI: 10.1007/s00277-013-1842-x

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