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LIFE Forschungszentrum

Publikationen 2014

Annibal A, Schubert K, Wagner U, Hoffmann RSchiller J, Fedorova M.
New covalent modifications of phosphatidylethanolamine by alkanals: mass spectrometry based structural characterization and biological effects. J Mass Spectrom 49(7) DOI: 1010.1002/jms.3373

Annibal A, Fedorova M, Schiller J, Hoffmann R, In vitro glycation and glycoxidation of phosphatidylethanolamines, J Freeradbiomed, 2014, DOI: org/10.1016/j.freeradbiomed.2014.10.734

Anthon C, Tafer H, Havgaard JH, Thomsen B, Hedegaard J,  Seemann SE, Pundhir S, Kehr S, Bartschat S, Nielsen M, Nielsen RO, Fredholm M, Stadler PF, Gorodkin J, Structured RNAs and synteny regions in the pig genome, BMC Genomics 2014, DOI: 10.1186/1471-2164-15-459.

Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, Gögele M, Anderson D, Broer L, Podmore C, Luan J, Kutalik Z, Sanna S, van der Meer P, Tanaka T, Wang F, Westra HJ, Franke L, Mihailov E, Milani L, Häldin J, Winkelmann J, Meitinger T, Thiery J … et al.
Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nat Commun. 5 DOI: 10.1038/ncomms5926

Binder H, Wirth H.
Analysis of large-scale OMIC data using Self Organizing Maps. Encyclopedia of Information Science and Technology Third Edition, M. Khosrow-Pour, Editor. IGI global. DOI:  10.4018/978-1-4666-5888-2.ch157

Bocsi J, Melzer S, Dähnert I, Tárnok A.
OMIP-023: 10-Color, 13 antibody panel for in-depth phenotyping of human peripheral blood leukocytes. Cytometry A 85(A) DOI: 10.1002/cyto.a.22505

Burkhardt J, Blume M, Petit-Teixeira E, Teixera VH, Seiner A, Quente E, Wolfram G, Scholz M, Pierlot C, Migliorini P, Bombardieri S, Balsa A, Westhovens R, Barrera P, Radstake T, Alves H, Bardin T, Prum B, Emmrich F, Cornelis F, Ahnert P, Kirsten H
Cellular Adhesion Gene SELP Is Associated with Rheumatoid Arthritis and Displays Differential Allelic Expresssion. PlosONE 9(8) DOI: 10.1371/journal.pone.0103872

Cakir V, Wirth H, Hopp L, Binder H.
miRNA expression landscapes in stem cells, tissue and cancer. Meth Mol Biol 1107 DOI: 10.1007/978-1-62703-748-8_17

Ceglarek U, Dittrich J, Helmschrodt C, Wagner K, Nofer JR, Thiery J, Becker S.
Preanalytical Standardization of Sphingosine-1-Phosphate, Sphinganine-1-Phosphate and Sphingosine Analysis in Human Plasma by Liquid Chromatography – Tandem Mass Spectrometry. Clin Chim Acta 435 DOI: 10.1016/j.cca.2014.04.010

Cousminer DL, ..., Körner A, ..., Kiess W, ...; Early Growth Genetics Consortium, Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Human Molecular Genetics 2014, DOI: 10.1093/hmg/ddu150

Derikx MH, Monique H, Kovacs P, Scholz M, Masson E, Chen JM, Ruffert C et al.. 
Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study. Gut 64(9) DOI: 10.1136/gutjnl-2014-307453.

Eszlinger M, Krogdahl A, Münz S, Rehfeld C, Precht Jensen EM, Ferraz C, Bösenberg E, Drieschner N, Scholz M, Hegedüs L, Paschke R
Impact of Molecular Screening for Point Mutations and Rearrangements in Routine Air-Dried Fine-Needle Aspiration Samples of Thyroid Nodules. Thyroid 24(2) DOI: 10.1089/thy.2013.0278

Gaede-Illig C, Zachariae S, Menzel C, Alfermann D
Körperliche Aktivitat erfassen – ein Vergleich vom IPAQ-SF und dem SenseWear Pro Armband. Dtsch Z Sportmed 65 DOI: 10.5960/dzsm.2014.130

Gasch M, Goroll T, Bauer M, Hinz D, Schütze N, Polte T, Kesper D, Simon J C, Hackermüller J, Lehmann I, Herberth G.
Generation of IL-8 and IL-9 Producing CD4+ T Cells Is Affected by Th17 Polarizing Conditions and AHR Ligands. Mediators Inflamm. 2014 DOI: .org/10.1155/2014/182549

Geissler J, Romanos M, Hegerl U, Hensch T
Hyperactivity and sensation seeking as autoregulatory attempts to stabilize brain arousal in ADHD and mania? Atten Defic Hyperact Disord 6(3) DOI: 10.1007/s12402-014-0144-z

Gross A, Schirm S, Scholz, M 
Ycasd - a tool for capturing and scaling data from graphical representations. BMC Bioinformatics 15 DOI: 10.1186/1471-2105-15-219

Hackermüller J, Reiche K, Otto C, Hösler N, Blumert C, Brocke-Heidrich K, et al. 
Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein coding RNAs. Genome Biol. 15(3) DOI: 10.1186/gb-2014-15-3-r48

Häntzsch M, Tolios A, Beutner F, Nagel D, Thiery J, Teupser D, Holdt LM.
Comparison of Whole Blood RNA Preservation Tubes and Novel Generation RNA Extraction Kits for Analysis of mRNA and MiRNA Profiles. PloS One 9(12) DOI 10.1371/journal.pone.0113298

Helmschrodt C, Becker S, Thiery J, Ceglarek U
Preanalytical standardization for reactive oxygen species derived oxysterol analysis in human plasma by liquid chromatography–tandem mass spectrometry. Biochem Biophys Res Comm 446(3) DOI: 10.1016/j.bbrc.2013.12.087

Hoffmann S, Otto C, Doose G, Tanzer A, Langenberger D, Christ S, Kunz M, Holdt L, Teupser D, Hackermüller J, Stadler PF
A multi-split mapping algorithm for circular RNA, splicing, trans-splicing, and fusion detection. Genome Biology 15(2) DOI: 10.1186/gb-2014-15-2-r34

Jawinski P, Sander C, Mauche N, Spada J, Häntzsch M, Burkhardt R, Hegerl U, Hensch T, CACNA1C gene variation is linked to EEG-vigilance regulation, Präsentation 18th biennial Meeting of the International Pharmaco-EEG Society, Leipzig, September 25-28 2014. Neuropsychobiology, 72(3).

Kassa TA, Luck T, Birru SK, Riedel-Heller SG. Sexuality and Sexual Reproductive Health of Disabled Young People in Ethiopia, Sex Transm Dis, 2014, DOI: 10.1097/OLQ.0000000000000182

Keller M, Schleinitz D, Müller I, Stumvoll M, Kovacs PBlüher M, Böttcher Y
Global DNA methylation level in human adipose tissue is related to fat distribution and glucose homeostasis. Diabetologia 57(11) DOI: 10.1007/s00125-014-3356-z

Kortz L, Dorow J, Ceglarek U
Liquid chromatography-tandem mass spectrometry for the analysis of eicosanoids and related lipids in human biological matrices: A review. J Chromatogr B Analyt Technol Biomed Life Sci. 964 DOI: 10.1016/j.jchromb.2014.01.046

Kucharik M, Hofacker IL, Stadler PF, Qin J. Basin Hopping Graph: a computational framework to characterize RNA folding landscapes. Bioinformatics 2014, vol.30 no 14 2014, pages 2009-2017, DOI: 10.1093/bioinformatics/btu156

Kuchlbauer V, Vogel M, Gausche R, Kapellen T, Rothe U, Vogel C, Pfäffle R, Kiess W. High birth weights but not excessive weight gain prior to manifestation are related to earlier onset of diabetes in childhood: 'accelerator hypothesis' revisited., Pediatric Diabetes, 2014, DOI: 10.1111/pedi.12107

Melzer S, Winter G, Jäger K, Hübschmann T, Hause G, Syrowatka F, Harms H, Tarnok A, Müller S
Cytometric patterns reveal growth states of Shewanella putrefaciens. microbial biotchn. 8(3) DOI: 10.1111/1751-7915.12154

Mueller B, Ahnert P, Burkhardt J, Brauer J, Czepezauer I, Quente E, et al. 
Genetic risk variants for dyslexia on chromosome 18 in a German cohort. Genes Brain Behav. 13(3) DOI: 10.1111/gbb.12118

Mueller K, Horstmann A, Möller HE, Anwander A, Lepsien J, Schroeter MLVillringer A, Pleger B., Obesity Associated Cerebral Gray and White Matter Alterations Are Interrelated in the Female Brain, PlosOne 2014, DOI:10.1371/journal.pone.0114206

Olbrich S, Tränker A, Chittka T, Hegerl U, Schönknecht P, Functional connectivity in major depression: increased phase synchronization between frontal cortical EEG-source estimates. PsychiatryRes, 2014, DOI: 10.1016/j.pscychresns.2014.02.010

Otto C, Stadler PF, Hoffmann S.
Lacking alignments? The next generation sequencing mapper segemehl revisited. Bioinformatics 30(13) DOI: 10.1093/bioinformatics/btu146

Polyakova M, Sonnabend N, Sander C, Mergl R, Schroeter ML,  Schroeder J, Schönknecht P
Prevalence of minor depression in elderly persons with and without mild cognitive impairment: A systematic review. J Aff Disord 152-154 DOI: 10.1016/j.jad.2013.09.016

Quinque EM, Karger S, Arelin K, Schroeter ML, Kratzsch J, Villringer A. 
Structural and func-tional MRI study of the brain, cognition and mood in long-term adequately treated Hash-imoto's thyroiditis. Psychoneuroendocrinology 42 DOI: 10.1016/j.psyneuen.2014.01.015

Rivarola-Duarte L, Otto C, Jühling F, Schreiber S, Bedulina D, Jakob L, Gurkov A, Axenov-Gribanov D, Sahyoun AH, Lucassen M, Hackermüller J, Hoffmann S, Sartoris F, Pörtner HO, Timofeyev M, Luckenbach T, Stadler PF
A first glimpse at the genome of the Baikalian amphipod Eulimnogammarus verrucosus. J Exp Zool B Mol Dev Evol 322(3) DOI 10.1002/jez.b.22560

Roesch K, Hasenclever D, Scholz M
Modelling Lymphoma Therapy and Outcome. Bull Math Biol 76 DOI: 10.1007/s11538-013-9925-3 2014: 76: 401-430

Roshyara NR, Kirsten H, Horn K, Ahnert P, Scholz M. 
Impact of pre-imputation SNP-filtering on genotype imputation results. BMC Genet. 15(1) DOI: 10.1186/s12863-014-0088-5

Roshyara NR, Scholz M. 
fcGENE: a versatile tool for processing and transforming SNP datasets. PLoS One (7) DOI: 10.1371/journal.pone.0097589

Schaefer A, Quinque EM, Kipping JA, Arélin K, Roggenhofer E, Frisch S, Villringer A, Mueller K, Schroeter ML
Early small vessel disease affects fronto-parietal and cerebellar hubs in close correlation with clinical symptoms – A resting-state fMRI study. J Cereb Blood Flow Metab 34(7) DOI: 10.1038/jcbfm.2014.70 

Schirm S, Engel C, Loeffler M, Scholz M. 
A combined model of human erythropoiesis and granulopoiesis under growth factor and chemotherapy treatment. Theor Biol Med Model 11 DOI: 10.1186/1742-4682-11-24

Schirm S, Engel C, Loeffler M, Scholz M.
Modelling chemotherapie effects on granulopoiesis. BMC Syst Biol DOI: 10.1186/s12918-014-0138-7

Schmid GL, Kässner F, Uhlig HH, Körner A, Kratzsch J, Händel N, Zepp FP, Kowalzik F, Laner A, Starke S, Wilhelm FK, Schuster S, Viehweger A, Hirsch W, Kiess W, Garten A
Sirolimus treatment of severe PTEN hamartoma tumor syndrome: case report and in vitro studies. Pediart Res 75(4) DOI: 10.1038/pr.2013.246

Schroeter ML, Laird AR, Chwiesko C, Deuschl C, Schneider E, Bzdok D, Eickhoff SB, Neumann J. 
Conceptualizing neuropsychiatric diseases with multimodal data-driven meta-analyses – The case of behavioral variant frontotemporal dementia. Cortex 57 DOI: 10.1016/j.cortex.2014.02.022

Schroeter ML, Mueller K, Arelin K, Sacher J, Holiga S, Kratzsch J, Luck T, Riedel-Heller S, Villringer A.
Serum neuron-specific enolase is related to cerebellar connectivity - A resting-state fMRI pilot study. J Neurotrauma 32(17) doi:10.1089/neu.2013.3163

Schroeter ML, Steiner J, Schoenknecht P, Mueller K. 
Further evidence for a role of S100B in mood disorders: A human gene expression mega-analysis. J Psychiatr Res 53 DOI: 10.1016/j.jpsychires.2014.02.021

Schuster S, Penke M, Gorski T, Petzold-Quinque S, Damm G, Gebhardt R, Kiess W, Garten A
Resveratrol Differentially Regulates NAMPT and SIRT1 in Hepatocarcinoma Cells and Primary Human Hepatocytes. PlosONE 9(3) DOI:10.1371/journal.pone.0091045

Spada J, Sander C, Burkhardt R, Häntzsch M, Mergl R, Scholz M, Hegerl U, Hensch T.
The association of objective sleep phenotypes with a functional polymorphism in the neuropeptide s receptor gene. PLoS One 9(6) DOI: 10.1371/journal.pone.0098789

Steinhoff K, Pierer M, Siegert J, Pigla U, Laub R, Hesse S, Seidel W, Sorger D, Seese A, Kuenstler JU, Pietzsch HJ, Lincke T, Rullmann M, Emmrich F,  Sabri O, Visualizing inflammation activity in rheumatoid arthritis with Tc-99 m Anti-CD4-mAb fragment scintigraphy, J NucMedBio, 2014, DOI: org/10.1016/j.nucmedbio.2013.12.018

Streitbürger DP, Pampel A, Krueger G, Lepsien J, Schroeter ML, Mueller K, Möller HE
Impact of image acquisition on voxel-based-morphometry investigations of age-related structural brain changes. Neuroimage 87 DOI: 10.1016/j.neuroimage. 2013.10.051

Then FS, Luck T, Luppa M, Arélin K, Schroeter ML, Engel C, Löffler M, Thiery J, Villringer A, Riedel-Heller SG
Association between mental demands at work and cognitive functioning in the general population - results of the health study of the Leipzig research center for civilization diseases (LIFE). J Occup Med Toxicol. (9) DOI: 10.1186/1745-6673-9-23

Then FS, Luck L, Luppa M, Thinschmidt M, Deckert S, Nieuwenhuijsen K, Seidler A, Riedel-Heller SG 
Systematic review of the effect of the psychosocial working environment on cognition and dementia. Occup Environ Med 71(5) DOI: 10.1136/oemed-2013-101760 

Tönjes A, Scholz M, Breitfeld J, Marzi C, Grallert H, Gross A, Ladenvall C, Schleinitz D, Krause K, Laurila E, Kriebel J, Thirand B, Rathmann W, Groop L, Prokopenko I, Isimaa B, Beutner F , Kratzsch J, Thiery J, Fasshauer M, Klöting N, Gieger C, Blüher M, Stumvoll M, Kovacs P
Genome Wide Meta-analysis Highlights the Role of Genetiv Variation in RARRES2 in the Regulation of Circulating Serum Chemerin. PLOS Genetics 10(12) DOI: 10.1371/journal.pgen.1004854

Walton E, Liu J, Hass J, White T, Scholz M, Roessner V, et al. 
MB-COMT promoter DNA methylation is associated with working-memory processing in schizophrenia patients and healthy controls. Epigenetics 9 (8) DOI: 10.4161/epi.29223

Weingärtner O, Baber R, Teupser D
Plant sterols in food: No consensus in guidelines. Biochem Biophys Res Commun. DOI: 10.1016/j.bbrc.2014.01.147

Wirth H, Cakir V, Hopp L, Binder H
Analysis of miRNA expression using machine learning. Meth Mol Biol 1107 DOI: 10.1007/978-1-62703-748-8_16

Zander J, Bruegel M, Kleinhempel A, Becker S, Petros S, Kortz L, Dorow J, Kratzsch J, Baber R, Ceglarek U, Thiery J, Teupser D
Effect of biobanking conditions on short-term stability of biomarkers in human serum and plasma. Clin Chem Lab Med 52(5) DOI: 10.1515/cclm-2013-0705

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