LIFE Health Study

Publikationen 2017

Al Arab M, Bernt M, Höner Zu Siederdissen C, Tout K, Stadler PF, Partially local three-way alignments and the sequence signatures of mitochondrial genome rearrangements., Algorithms Mol Biol. 2017;12:22. DOI: 10.1186/s13015-017-0113-0

Albrecht F, Bisenius S, Morals Schaack R, Neumann J, Schroeter ML, Disentangling the neural correlates of corticobasal syndrome and corticobasal degeneration with systematic and quantitative ALE meta-analyses., NPJ Parkinsons Dis. 2017;3:12. DOI: 10.1038/s41531-017-0012-6

Alkan F, Wenzel A, Palasca O, Kerpedjiev P, Rudebeck AF, Stadler PF, Hofacker IL, Gorodkin J, RIsearch2: suffix array-based large-scale prediction of RNA-RNA interactions and siRNA off-targets,  Nucleic Acids Res. 2017,  pii: gkw1325. DOI: 10.1093/nar/gkw1325

Becker S, Kinny-Köster B, Bartels M, Scholz M, Seehofer D, Berg T, Engelmann C, Thiery JCeglarek U, Kaiser T, Low sphingosine-1-phosphate plasma levels are predictive for increased mortality in patients with liver cirrhosis., PLoS One. 2017;12(3):e0174424. DOI: 10.1371/journal.pone.0174424

Berkemer SJ, Hoffmann A, Murray CRA, Stadler PFSMORE: Synteny Modulator of Repetitive Elements., Life (Basel). 2017; 7(4). pii: E42. DOI: 10.3390/life7040042

Beyer F, Kharabian Masouleh S, Huntenburg JM, Lampe L, Luck T, Riedel-Heller SG, Loeffler MSchroeter ML, Stumvoll M, Villringer A, Witte AV, Higher body mass index is associated with reduced posterior default mode connectivity in older adults., Hum Brain Mapp. 2017; DOI: 10.1002/hbm.23605

Binder S, Hösler N, Riedel D, Zipfel I, Buschmann T, Kämpf C, Reiche K, Burger R, Gramatzki M, Hackermüller J, Stadler PFHorn F, STAT3-induced long noncoding RNAs in multiple myeloma cells display different properties in cancer., Sci Rep. 2017; 7(1):7976. DOI: 10.1038/s41598-017-08348-5.

Bisenius S, Mueller K, Diehl-Schmid J, Fassbender K, Grimmer T, Jessen F, Kassubek J, Kornhuber J, Landwehrmeyer B, Ludolph A, Schneider A, Anderl-Straub S, Stuke K, Danek A, Otto M, Schroeter ML; FTLDc study group, Predicting primary progressive aphasias with support vector machine approaches in structural MRI data., Neuroimage Clin. 2017;14:334-343. DOI: 10.1016/j.nicl.2017.02.003

Blücher C, Stadler SC, Obesity and Breast Cancer: Current Insights on the Role of Fatty Acids and Lipid Metabolism in Promoting Breast Cancer Growth and Progression., Front Endocrinol (Lausanne). 2017;8:293. DOI: 10.3389/fendo.2017.00293

Buchmann N, Scholz M, Lill CM, Burkhardt R, Eckardt R, Norman K, Loeffler M, Bertram L, Thiery J, Steinhagen-Thiessen E, Demuth I., Association between lipoprotein(a) level and type 2 diabetes: no evidence for a causal role of lipoprotein(a) and insulin., Acta Diabetol. 2017, DOI: 10.1007/s00592-017-1036-4

Buerger F, Burkhardt R, Lipid metabolism: from genetic loci to functional understanding., Curr Opin Lipidol. 2017;28(1):81-82. DOI: 10.1097/MOL.0000000000000380.

Buerger F, Müller S, Ney N, Weiner J, Heiker JT, Kallendrusch S, Kovacs P, Schleinitz D, Thiery J, Stadler SC, Burkhardt R, Depletion of Jmjd1c impairs adipogenesis in murine 3T3-L1 cells, Biochim Biophys Acta. 2017; pii: S0925-4439(17)30148-5. DOI: 10.1016/j.bbadis.2017.05.011

Bussler S, Penke M, Flemming G, Elhassan YS, Kratzsch J, Sergeyev E, Lipek T, Vogel M, Spielau U, Körner A, de Giorgis T, Kiess W, Novel Insights in the Metabolic Syndrome in Childhood and Adolescence., Horm Res Paediatr. 2017, DOI: 10.1159/000479510

Bussler S, Vogel M, Pietzner D, Harms K, Buzek T, Penke M, Händel N, Körner A, Baumann U, Kiess W, Flemming G., New pediatric percentiles of liver enzyme serum levels (ALT, AST, GGT): Effects of age, sex, BMI and pubertal stage., Hepatology. 2017; DOI: 10.1002/hep.29542

Chierchia G, Parianen Lesemann FH, Snower D, Vogel M, Singer T, “Caring Cooperators and Powerful Punishers: Differential Effects of Induced Care and Power Motivation on Different Types of Economic Decision Making”. Scientific Reports 7: 11068., DOI: 10.1038/s41598-017-11580-8

Dittrich J, Ceglarek U, Absolute Quantification of Middle- to High-Abundant Plasma Proteins via Targeted Proteomics., Methods Mol Biol. 2017;1619:417-430. DOI: 10.1007/978-1-4939-70575_29

Dittrich J, Adam M, Maas H, Hecht M, Reinicke M, Ruhaak R, Cobbaert C, Engel C, Wirkner K, Löffler M, Thiery J, Ceglarek U, Targeted on-line SPE-LC-MS/MS Assay for the quantitation of twelve apolipoproteins from human blood., Proteomics. 2017 ; DOI: 10.1002/pmic.201700279

Fabian S, Gelbrich B, Hiemisch A, Kiess W, Hirsch C; LIFE Child study team, Impact of overbite and overjet on oral health-related quality of life of children and adolescents., J Orofac Orthop. 2017, DOI: 10.1007/s00056-017-0114-0

Gesing J, Scheuermann K, Wagner IV, Löffler D, Friebe D, Kiess W, Schuster V, Körner A, NAMPT serum levels are selectively elevated in acute infectious disease and in acute relapse of chronic inflammatory diseases in children., PLoS One. 2017;12(8):e0183027. DOI: 10.1371/journal.pone.0183027

Glock F, Vogel M, Naumann S, Kuehnapfel A, Scholz M, Hiemisch A, Kirsten T, Rieger K, Koerner A, Loeffler M, Kiess W, Validity and intra-observer reliability of three-dimensional scanning compared to conventional anthropometry for children and adolescents from a population-based cohort study., Pediatr Res. 2017,  DOI: 10.1038/pr.2016.274. 

Glock F, Scholz M, Kuehnapfel A, Kiess W, Validity and reliability of three-dimensional scanning compared with conventional anthropometry for children and adolescents-response to the rebuttal by Sabour, Pediatr Res. 2017, DOI: 10.1038/pr.2017.76

Gross A, Tönjes A, Scholz M, On the impact of relatedness on SNP association analysis., BMC Genet. 2017;18(1):104. DOI: 10.1186/s12863-017-0571-x.

Hellmuth M, Hernandez-Rosales M, Long Y, Stadler PFInferring phylogenetic trees from the knowledge of rare evolutionary events., J Math Biol. 2017; DOI: 10.1007/s00285-017-1194-6

Herrmann J, Vogel M, Pietzner D, Kroll E, Wagner OSchwarz S, Müller E, Kiess W, Richter M, Poulain TFactors associated with the emotional health of children: high family income as a protective factor., Eur Child Adolesc Psychiatry. 2017; DOI: 10.1007/s00787-017-1049-0

Heser K, Luck T, Röhr S, Wiese B, Kaduszkiewicz H, Oey A, Bickel H, Mösch E, Weyerer S, Werle J, Brettschneider C, König HH, Fuchs A, Pentzek M, van den Bussche H, Scherer M, Maier W, Riedel-Heller SG, Wagner M; (shared last authorship) for the AgeCoDe & AgeQualiDe study groups., Potentially inappropriate medication: Association between the use of antidepressant drugs and the subsequent risk for dementia., J Affect Disord. 2017; 226:28-35. DOI: 10.1016/j.jad.2017.09.016

Hiemisch A, Stöbel-Richter Y, Grande G, Brähler E, Kiess W[Are We Really as Happy as We Think We are? A Critical Examination of Work Satisfaction in a University Pediatric Hospital]., Gesundheitswesen. 2017, DOI: 10.1055/s-0043-121873.

Hinz A, Glaesmer H, Brähler E, Löffler M, Engel C, Enzenbach C, Hegerl U, Sander C,Sleep quality in the general population: psychometric properties of the Pittsburgh Sleep Quality Index, derived from a German community sample of 9284 people, Sleep Medicine 2017, 30 , 57-63, DOI: org/10.1016/j.sleep.2016.03.008

Hinz A, Sander C, Glaesmer H, Brähler E, Zenger M, Hilbert A, Kocalevent R-D, Optimism and pessimism in the general population: Psychometric properties of the Life Orientation Test (LOT-R). International Journal of Clinical and Health Psychology, 2017, 17, 161-170. DOI:org/10.1016/j.ijchp.2017.02.003

Hinz A, Ernst J, Glaesmer H, Brähler E, Rauscher FG, Petrowski K, Kocalevent RD, Frequency of somatic symptoms in the general population: Normative values for the Patient Health Questionnaire-15 (PHQ-15), Journal of Psychosomatic Research, 96, 27-31., DOI:org/10.1016/j.jPsychores.2016.12.017

Hoffmann A, Fallmann J, Mörl M, Stadler PF, Amman F, Accurate Mapping of tRNA Reads., Bioinformatics. 2017, DOI: 10.1093/bioinformatics/btx756

Hoffmann M, Gebauer S, Nüchter M, Baber R, Ried J, von Bergen M, Kiess W, Endocrine disruptors : Evidence from epidemiological studies necessitates a critical review of model systems, Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2017, DOI: 10.1007/s00103-017-2551-8

Jahreis S, Trump S, Bauer M, Bauer T, Thürmann L, Feltens R, Wang Q, Gu L, Grützmann K, Röder S, Averbeck M, Weichenhan D, Plass C, Sack U, Borte M, Dubourg V, Schüürmann G, Simon JC, von Bergen M, Hackermüller J, Eils R, Lehmann I, Polte T, Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications, Journal of Allergy and Clinical ImmunologyDOI: 10.1016/j.jaci.2017.03.017

Jawinski P, Kittel J, Sander C, Huang J, Spada J, Ulke C, Wirkner K, Hensch T, Hegerl U, Recorded and reported sleepiness: The association between brain arousal in resting state and subjective daytime sleepiness, Sleep 2017, DOI: 10.1093/sleep/zsx099  

Jost L, Fuchs M, Loeffler M, Thiery J, Kratzsch J, Berger T, Engel C, Associations of Sex Hormones and Anthropometry with the Speaking Voice Profile in the Adult General Population., J Voice. 2017, pii: S0892-1997(17)30216-3. DOI: 10.1016/j.jvoice.2017.06.011

Junge J, Engel CVogel M, Naumann S, Löffler M, Thiery J, Kratzsch J, Kiess W, Körner A, Neck circumference is similarly predicting for impairment of glucose tolerance as classic anthropometric parameters among healthy and obese children and adolescents., J Pediatr Endocrinol Metab. 2017; pii: /j/jpem.ahead-of-print/jpem-2017-0079/jpem-2017-0079.xml. DOI: 10.1515/jpem-2017-0079.

Kaiser T, Kinny-Köster B, Bartels M, Berg T, Scholz M, Engelmann C, Seehofer D, Becker S , Ceglarek U, Thiery J, Cholesterol esterification in plasma as a biomarker for liver function and prediction of mortality, BMC Gastroenterol. 2017;17(1):57. DOI: 10.1186/s12876-017-0614-9

Kalenda A, Landgraf K, Löffler D, Kovacs P, Kiess W, Körner A, The BDNF Val66Met polymorphism is associated with lower BMI, lower postprandial glucose levels and elevated carbohydrate intake in children and adolescents., Pediatr Obes. 2017; DOI: 10.1111/ijpo.12238.

Keß A, Spielau U, Beger C, Gausche R, Vogel M, Lipek T, Körner A, Pfäffle R, Kiess W., Further stabilization and even decrease in the prevalence rates of overweight and obesity in German children and adolescents from 2005 to 2015: a cross-sectional and trend analysis., Public Health Nutr. 2017:1-9. DOI: 10.1017/S1368980017002257.

Kharabian Masouleh S, Beyer F, Lampe L, Loeffler M, Luck T, Riedel-Heller SG, Schroeter ML, Stumvoll M, Villringer A, Witte AV, Gray matter structural networks are associated with cardiovascular risk factors in healthy older adults., J Cereb Blood Flow Metab. 2017 , 271678X17729111. DOI: 10.1177/0271678X17729111

Kirsten T,  Kiel A,  Rühle M, Wagner J, Metadata Management for Data Integrationin Medical Sciences  - Experiences from the LIFE Study - , btw-Kongress Stuttgart, 2017

Kirsten T, Blumberg J, Ivanova G, Dietrich P, Engel C, Löffler M, Kiess W, Research in Progress on Integrating Health and Environmental Data in Epidemiological Studies, Business Information Systems Workshops, 2017,  S. 347-354, DOI: 10.1007/978-3-319-52464-1_32

Kliem S, Schmidt R, Vogel M, Hiemisch A, Kiess W, Hilbert A., An 8-item short form of the Eating Disorder Examination-Questionnaire adapted for children (ChEDE-Q8)., Int J Eat Disord. 2017, DOI: 10.1002/eat.22658

Kornej J, Luck T, Zeynalova S, Löffler M, Riedel-Heler S, Husser D, Assocation between PR interval prolongation, atrial fibrillation and cognitive function: insights from the LIFE-Adult-Study, Gesundheitswesen 2017; 79(08/09): 656-804, DOI: 10.1055/s-0037-1605961

Kornej J, Zeynalova S, Loeffler M, Tautenhahn S, Engel C, Thiery J, Wirkner K, Burkhardt R,  Baber R, Hagendorff A, Husser D, Association of PR interval with echocardiographic parameters and biomarkers: insights from the LIFE-Adult-Study, European Heart Journal, 2017, 38(1); DOI: 10.1093/eurheartj/ehx493.P550

Kretzmer H, Otto C, Hoffmann S, BAT: Bisulfite Analysis Toolkit: BAT is a toolkit to analyze DNA methylation sequencing data accurately and reproducibly. It covers standard processing and analysis steps from raw read mapping up to annotation data integration and calculation of correlating DMRs., F1000Res. 2017;6:1490. DOI: 10.12688/f1000research.12302.1

Kuchenbaecker KB, Hopper JL, Barnes DR, Phillips KA, Mooij TM, Roos-Blom MJ, Jervis S7, van Leeuwen FE, Milne RL, Andrieu N, Goldgar DE, Terry MB, Rookus MA, Easton DF, Antoniou AC, BRCA1 and BRCA2 Cohort Consortium, McGuffog L, Evans DG, Barrowdale D, Frost D, Adlard J, Ong KR, Izatt L, Tischkowitz M, Eeles R, Davidson R, Hodgson S, Ellis S, Nogues C, Lasset C, Stoppa-Lyonnet D, Fricker JP, Faivre L, Berthet P, Hooning MJ, van der Kolk LE, Kets CM, Adank MA, John EM, Chung WK, Andrulis IL, Southey M, Daly MB, Buys SS, Osorio A, Engel C, Kast K, Schmutzler RK, Caldes T, Jakubowska A, Simard J, Friedlander ML, McLachlan SA, Machackova E, Foretova L, Tan YY, Singer CF, Olah E, Gerdes AM, Arver B, Olsson H, Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers., JAMA. 2017;317(23):2402-2416. DOI: 10.1001/jama.2017.7112

Kuehnapfel A,  Ahnert P, Loeffler M, Scholz M, Body surface assessment with 3D laser-based anthropometry: reliability, validation, and improvement of empirical surface formulae, Eur J Appl Physiol. 2017, DOI: 10.1007/s00421-016-3525-5.

Kuehnapfel A, Schwarzenberger F, Scholz M, On the Conditional Power in Survival Time Analysis Considering Cure Fractions., Int J Biostat. 2017,  pii: /j/ijb.ahead-of-print/ijb-2015-0073/ijb-2015-0073.xml., DOI: 10.1515/ijb-2015-0073

Kynast J, Lampe L, Luck T, Frisch S, Arelin K, Hoffmann KT, Loeffler M, Riedel-Heller SG, Villringer A, Schroeter ML, White matter hyperintensities associated with small vessel disease impair social cognition beside attention and memory., J Cereb Blood Flow Metab. 2017 1:271678X17719380. DOI: 10.1177/0271678X17719380

Lin YC, Groß A, Kirsten T, Integration and visualization of spatial data in LIFE, it - Information Technology, 2017, 59(4), 161-170, DOI: 10.1515/itit-2016-0025

Löffler A, Luck T, Then FS, Luck-Sikorski C, Pabst A, Kovacs P, Böttcher Y, Breitfeld J, Tönjes A, Horstmann A, Löffler M, Engel C, Thiery J, Villringer A, Stumvoll M, Riedel-Heller SG, Effects of psychological eating behaviour domains on the association between socio-economic status and BMI., Public Health Nutr. 2017:1-7. DOI: 10.1017/S1368980017001653.

Loeffler-Wirth H, Vogel M, Kirsten T, Glock F, Poulain T, Körner A, Loeffler M, Kiess W, Binder H, Body typing of children and adolescents using 3D-body scanning., PLoS One. 2017;12(10):e0186881. DOI: 10.1371/journal.pone.0186881

Löffler-Wirth H, Frenzel A, Löffler M, Binder H, Exploration of Human Ageing by 3D-Laser Scanning Anthropometry, Proceedings of 3DBODY.TECH 2017, DOI: 10.15221/17.026

Lott SC, Wolfien M, Riege K, Bagnacani A, Wolkenhauer O, Hoffmann S, Hess WR., Customized workflow development and data modularization concepts for RNA-Sequencing and metatranscriptome experiments., J Biotechnol. 2017, pii: S0168-1656(17)31499-2. DOI: 10.1016/j.jbiotec.2017.06.1203.

Luck T, Rodriguez FS, Wiese B, van der Leeden C, Heser K, Bickel H, In der Schmitten J, Koenig HH, Weyerer S, Mamone S, Mallon T, Wagner M, Weeg D, Fuchs A, Brettschneider C, Werle J, Scherer M, Maier W, Riedel-Heller SG,  AgeCoDe & AgeQualiDe study group, Advance directives and power of attorney for health care in the oldest-old - results of the AgeQualiDe study., BMC Geriatr. 2017;17(1):85. DOI: 10.1186/s12877-017-0482-8.

Lukowski SW, Lloyd-Jones LR, Holloway A, Kirsten H, Hemani G, Yang J, Small K, Zhao J, Metspalu A, Dermitzakis ET, Gibson G, Spector TD, Thiery J, Scholz M, Montgomery GW, Esko T, Visscher PM, Powell JE, Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood., Nat Commun. 2017;8(1):483. DOI: 10.1038/s41467-017-00473-z

Machné R, Murray DB, Stadler PFSimilarity-Based Segmentation of Multi-Dimensional Signals.,Sci Rep. 2017;7(1):12355. DOI: 10.1038/s41598-017-12401-8. 

Meyer S, Mueller K, Stuke K, Bisenius S, Diehl-Schmid J, Jessen F, Kassubek J, Kornhuber J, Ludolph AC, Prudlo J, Schneider A, Schuemberg K, Yakushev I, Otto M, Schroeter ML; FTLDc Study Group, Predicting behavioral variant frontotemporal dementia with pattern classification in multi-center structural MRI data, Neuroimage Clin. 2017 ;14:656-662. DOI: 10.1016/j.nicl.2017.02.001

Michailidou K, Lindström S, Dennis J, Beesley J, Hui S, Kar S ,…….., Durcan L, Dwek M, Eccles DM, Ekici AB, Eliassen AH, Ellberg C, Elvira M, Engel C, Eriksson M, Fasching PA ,…, García-Closas M, Schmidt MK, Chanock SJ, Dunning AM, Edwards SL, Bader GD, Chenevix-Trench G, Simard J, Kraft P, Easton DF, Association analysis identifies 65 new breast cancer risk loci., Nature. 2017; DOI: 10.1038/nature24284

Milne RL, Kuchenbaecker KB, Michailidou K, Beesley J, Kar S, Lindström S, Hui S, Lemaçon A, ………., Eilber U, Ejlertsen B, Ekici AB, Eliassen AH; EMBRACE, Engel C, Eriksson M, Fachal L, Faivre L, Fasching PA, Faust U, Figueroa J, ……….., Mannermaa A, Olsson H, Teixeira MR, Stone J, Offit K, Ottini L, Park SK, Thomassen M, Hall P, Meindl A, Schmutzler RK, Droit A, Bader GD, Pharoah PDP, Couch FJ, Easton DF, Kraft P, Chenevix-Trench G, García-Closas M, Schmidt MK, Antoniou AC, Simard J., Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer, Nat Genet. 2017, DOI: 10.1038/ng.3785

Müller B, Schaadt G, Boltze J, Emmrich F; LEGASCREEN Consortium, Skeide MA, Neef NE, Kraft I, Brauer J, Friederici AD, Kirsten H, Wilcke A; ATP2C2 and DYX1C1 are putative modulators of dyslexia-related MMR., Brain Behav. 2017;7(11):e00851. DOI: 10.1002/brb3.851

Neef NE, Müller B, Liebig J, Schaadt G, Grigutsch M, Gunter TC, Wilcke A, Kirsten H, Skeide MA, Kraft I, Kraus N, Emmrich F, Brauer J, Boltze J, Friederici AD, Dyslexia risk gene relates to representation of sound in the auditory brainstem., Dev Cogn Neurosci. 2017;24:63-71. DOI: 10.1016/j.dcn.2017.01.008

Paech C, Liebold A,Gebauer RA, Wagner F, Vogel M, Kirsten T, Schauff M, Hiemisch A, Dähnert I, Kiess W, Körner A, Relative QT interval prolongation and electrical inhomogeneity of cardiac repolarization in childhood obesity, Progress in Pediatrc Cardiology 2017, 47, 64-67, DOI: 10.1016/j.ppedcard.2017.08.001

Paech C, Anhalt M, Gebauer RA, Wagner M, Vogel M, Kirsten T, Weidenbach M, Kiess W, Dähnert I, Körner A, New normal limits for pediatric ECG in childhood obesity? Influence of childhood obesity on the ECG, Progress in Pediatrc Cardiology 2017, 48, 119-123, DOI: 10.1016/j.ppedcard.2017.11.002 

Polyakova M, Schlögl H, Sacher J, Schmidt-Kassow M, Kaiser J, Stumvoll M, Kratzsch J, Schroeter ML, Stability of BDNF in Human Samples Stored Up to 6 Months and Correlations of Serum and EDTA-Plasma Concentrations., Int J Mol Sci. 2017;18(6). pii: E1189. DOI: 10.3390/ijms18061189.

Pott J, Burkhardt R, Beutner F, Horn K, Teren A, Kirsten H, Holdt LM, Schuler G, Teupser D, Loeffler M, Thiery J, Scholz M ,Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery, Atherosclerosis. 2017;259:32-40. DOI:10.1016/j.atherosclerosis.2017.02.018

Poulain T, Baber R, Vogel M, Pietzner D, Kirsten T, Jurkutat A, Hiemisch A, Hilbert A, Kratzsch J, Thiery J, Fuchs M, Hirsch C, Rauscher FG, Loeffler M, Körner A, Nüchter M, Kiess W, LIFE Child study team., The LIFE Child study: a population-based perinatal and pediatric cohort in Germany., Eur J Epidemiol. 2017,  DOI: 10.1007/s10654-016-0216-9.

Raulien N, Friedrich K, Strobel S, Rubner S, Baumann S, von Bergen M, Körner A, Krueger M, Rossol M, Wagner U, Fatty Acid Oxidation Compensates for Lipopolysaccharide-Induced Warburg Effect in Glucose-Deprived Monocytes., Front Immunol. 2017;8:609. DOI: 10.3389/fimmu.2017.00609.

Reinhold O, Wittwer M, Alt R, Kirsten T, Kiess W, Exploring Context from the Consumer Perspective: Insights from eBusiness and Health Care., Lecture Notes in Business Information Processing, vol 263. 340-346, Springer, Cham, DOI: 10.1007/978-3-319-52464-1_31

Rodriguez FS, Schroeter ML, Witte AV, Engel C, Löffler M, Thiery J, Villringer A, Luck T, Riedel-Heller SG, Could High Mental Demands at Work Offset the Adverse Association Between Social Isolation and Cognitive Functioning? Results of the Population-Based LIFE-Adult-Study., Am J Geriatr Psychiatry. 2017, pii: S1064-7481(17)30337-8. DOI: 10.1016/j.jagp.2017.05.014

Rodriguez FSSchroeter ML, Arélin K, Witte AV, Baber R, Burkhardt R, Engel C, Löffler M, Thiery J, Villringer A, Luck T, Riedel-Heller SG, APOE e4-Genotype and Lifestyle Interaction on Cognitive Performance: Results of the LIFE-Adult-Study., Health Psychol. 2017, DOI: 10.1037/hea0000515

Roehr S, Pabst A, Luck T, Riedel-Heller SG, Secular trends in the incidence of dementia in high-income countries: a protocol of a systematic review and a planned meta-analysis., BMJ Open. 2017; 7(4):e013630. DOI: 10.1136/bmjopen-2016-013630.

Roehr S, Luck T, Pabst A, Bickel H, König HH, Lühmann D, Fuchs A, Wolfsgruber S, Wiese B, Weyerer S, Mösch E, Brettschneider C, Mallon T, Pentzek M, Wagner M, Mamone S, Werle J, Scherer M, Maier W, Jessen F, Riedel-Heller SG; AgeCoDe study group., Subjective cognitive decline is longitudinally associated with lower health-related quality of life., Int Psychogeriatr. 2017:1-12. DOI: 10.1017/S1041610217001399

Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C1, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP; Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut. 2017. pii: gutjnl-2017-314454. DOI: 10.1136/gutjnl-2017-314454

Scharlau F, Pietzner D, Vogel M, Gaudl A, Ceglarek U, Thiery J, Kratzsch J, Hiemisch A, Kiess W, Evaluation of hair cortisol and cortisone change during pregnancy and the association with self-reported depression, somatization, and stress symptoms., Stress. 2017; 26:1-8. DOI: 10.1080/10253890.2017.1392507

Schlager S, Vujic N, KorbeliusM, Duta-Mare M,  Dorow J, Leopold C,  Rainer S, Wegscheider M, Reicher H, Ceglarek U,  Sattler W, Radovic B, Kratky D, Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages, J Oncotarget 2017, DOI: 10.18632/oncotarget.16673

Schmidt CO, Krabbe C, Schössow J, Berger K, Enzenbach C, Kamtsiuris P, Schöne G, Houben R, Meisinger C, Bamberg F, Hendel T, Selder S, Nonnemacher M, Moebus S, Stausberg J, Qualitätsstandards für epidemiologische Kohortenstudien, Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2017, DOI: 10.1007/s00103-017-2658-y

Schmidt J, Guder U, Kreuz M, Löffler M, Kiess W, Hirsch C, Ziebolz D, Haak R, AMMP-8 in correlation to caries and periodontal condition in adolescents-results of the epidemiologic LIFE child study., Clin Oral Investig. 2017, DOI: 10.1007/s00784-017-2132-0

Sen R, Doose G, Stadler PF, Rare Splice Variants in Long Non-Coding RNAs, Noncoding RNA. 2017; 3(3). pii: E23. DOI: 10.3390/ncrna3030023.

Sierau S, Brand T, Manly JT, Schlesier-Michel A, Klein AM, Andreas A, Garzón LQ, Keil J, Binser MJ, von Klitzing K, White LO, A Multisource Approach to Assessing Child Maltreatment From Records, Caregivers, and Children., Child Maltreat. 2017;22(1):45-57. DOI: 10.1177/1077559516675724.

Stadelmann S, Jaeger S, Matuschek T, Bae YJ, von Klitzing K, Klein AM, Döhnert M., Endocrinological and subjective stress responses in children with depressive, anxiety, or externalizing disorders., Dev Psychopathol. 2017:1-18. DOI: 10.1017/S0954579417001146

Stanik J, Kratzsch J, Landgraf K, Scheuermann K, Spielau U, Gausche R, Gasperikova D, Kiess W, Körner A, Concordance of bioactive vs. total immunoreactive serum leptin levels in children with severe early onset obesity., PLoS One. 2017;12(5):e0178107. DOI: 10.1371/journal.pone.0178107

Stanikova D, Luck T, Bae YJ, Thiery J, Ceglarek U, Engel C, Enzenbach C, Wirkner K, Stanik J, Kratzsch J, Riedel-Heller SG, Increased estrogen level can be associated with depression in males., Psychoneuroendocrinology. 2017;87:196-203. DOI: 10.1016/j.psyneuen.2017.10.025

Stein J, Röhr S, Luck T, Löbner M, Riedel-Heller SG, Indication and Evidence of Internationally Developed Online Coaches as Intervention for Mental Illness - a Meta-Review, Psychiatr Prax. 2017, DOI: 10.1055/s-0043-117050

Teren A, Kirsten H, Beutner F, Scholz M, Holdt LM, Teupser D, Gutberlet M, Thiery J, Schuler G, Eitel I, Alteration of Multiple Leukocyte Gene Expression Networks is Linked with Magnetic Resonance Markers of Prognosis After Acute ST-Elevation Myocardial Infarction., Sci Rep. 2017;7:41705. DOI: 10.1038/srep41705.

Terliesner N, Vogel M, Steighardt A, Gausche R, Henn C, Hentschel J, Kapellen T, Klamt S, Gebhardt J, Kiess W, Prenzel F., Cystic-fibrosis related-diabetes (CFRD) is preceded by and associated with growth failure and deteriorating lung function., J Pediatr Endocrinol Metab. 2017, pii: /j/jpem.ahead-of-print/jpem-2017-0005/jpem-2017-0005.xml. doi: 10.1515/jpem-2017-0005

Tönjes A, Scholz M, Krüger J, Krause K, Schleinitz D, Kirsten H, Gebhardt C, Marzi C, Grallert H, Ladenvall C, Heyne H, Laurila E, Kriebel J, Meisinger C, Rathmann W, Gieger C, Groop L, Prokopenko I, Isomaa B, Beutner F, Kratzsch J, Fischer-Rosinsky A, Pfeiffer A, Krohn K, Spranger J, Thiery J, Blüher M, Stumvoll M, Kovacs P, Genome wide meta-analysis identifies novel determinants of circulating serum progranulin., Hum Mol Genet. 2017; 27(3); 546-558; DOI: 10.1093/hmg/ddx413.

Treudler R, Zeynalova S, Walther F, Engel C, Simon JC, Atopic dermatitis is associated with autoimmune but not with cardiovascular comorbidities in a random sample of the general population in Leipzig, Germany., J Eur Acad Dermatol Venereol. 2017, DOI: 10.1111/jdv.14495

Valach M, Moreira S, Hoffmann S, Stadler PF, Burger G, Keeping it complicated: Mitochondrial genome plasticity across diplonemids, Sci Rep. 2017;7(1):14166. DOI: 10.1038/s41598-017-14286-z.

Vogel M, Kirsten T, Kratzsch J, Engel C, Kiess W., A combined approach to generate laboratory reference intervals using unbalanced longitudinal data.,  J Pediatr Endocrinol Metab. 2017,  pii: /j/jpem.ahead-of-print/jpem-2017-0171/jpem-2017-0171.xml. DOI: 10.1515/jpem-2017-0171

Wagner M, Scheibe P, Francke M, Zimmerling B, Frey K, Vogel M, Luckhaus S, Wiedemann P, Kiess W, Rauscher FG, Automated detection of the choroid boundary within OCT image data using quadratic measure filters, J of Biomedical Optics, 2017, 22(2), DOI: 10.1117/1.JBO.22.2.025004

Wang M, Elze T, Li D, Baniasadi N, Wirkner K, Kirsten T, Thiery J, Loeffler M, Engel C, Rauscher FG, Age, ocular magnification, and circumpapillary retinal nerve fiber layer thickness., J Biomed Opt. 2017;22(12):1-19. DOI: 10.1117/1.JBO.22.12.121718

Weithase A, Vogel M, Kiep H, Schwarz S, Meißner L, Herrmann J, Rieger K, Koch C, Schuster V, Kiess W, Quality of and Attendance at Healthy Child Clinics in Germany, Dtsch Med Wochenschr. 2017;142(8):e42-e50. DOI: 10.1055/s-0043-100841

Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, Li M, Yao J, Sim X, Hong J, Chu AY, Zhang W, Wang X, Chen P, Maruthur NM, Porneala BC, Sharp SJ, Jia Y, Kabagambe EK, Chang LC, Chen WM, Elks CE, Evans DS, Fan Q, Giulianini F, Go MJ, Hottenga JJ, Hu Y, Jackson AU, Kanoni S, Kim YJ, Kleber ME, Ladenvall C, Lecoeur C, Lim SH, Lu Y, Mahajan A, Marzi C, Nalls MA, Navarro P Nolte IM, Rose LM, Rybin DV, Sanna S, Shi Y, Stram DO, Takeuchi F, Tan SP, van der Most PJ, Van Vliet-Ostaptchouk JV, Wong A, Yengo L, Zhao W, Goel A, Martinez Larrad MT, Radke D, Salo P, Tanaka T, van Iperen EPA, Abecasis G, Afaq S, Alizadeh BZ, Bertoni AG, Bonnefond A, Böttcher Y, Bottinger EP, Campbell H, Carlson OD, Chen CH, Cho YS, Garvey WT, Gieger C, Goodarzi MO, Grallert H, Hamsten A, Hartman CA, Herder C, Hsiung CA, Huang J, Igase M, Isono M, Katsuya T, Khor CC, Kiess W, Kohara K, Kovacs P, Lee J, Lee WJ, Lehne B, Li H, Liu J, Lobbens S, Luan J, Lyssenko V, Meitinger T, Miki T, Miljkovic I, Moon S, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nauck M, Pankow JS, Polasek O, Prokopenko I, Ramos PS, Rasmussen-Torvik L, Rathmann W, Rich SS, Robertson NR, Roden M, Roussel R, Rudan I, Scott RA,  Scott WR, Sennblad B, Siscovick DS, Strauch K, Sun L, Swertz M, Tajuddin SM, Taylor KD, Teo YY, Tham YC, Tönjes A, Wareham NJ, Willemsen G, Wilsgaard T, Hingorani AD; EPIC-CVD Consortium; EPIC-InterAct Consortium; Lifelines Cohort Study, Egan J, Ferrucci L, Hovingh GK, Jula A, Kivimaki M,  Kumari M, Njølstad I, Palmer CNA, Serrano Ríos M, Stumvoll M, Watkins H, Aung T, Blüher M, Boehnke M, Boomsma DI, Bornstein SR, Chambers JC, Chasman DI, Chen YI, Chen YT, Cheng CY, Cucca F, de Geus EJC, Deloukas P, Evans MK, Fornage M, Friedlander Y, Froguel P, Groop L, Gross MD, Harris TB, Hayward C, Heng CK, Ingelsson E, Kato N, Kim BJ, Koh WP, Kooner JS, Körner A, Kuh D, Kuusisto J, Laakso M, Lin X, Liu Y, Loos RJF, Magnusson PKE, März W, McCarthy MI, Oldehinkel AJ, Ong KK, Pedersen NL, Pereira MA, Peters A, Ridker PM, Sabanayagam C, Sale M,  Saleheen D, Saltevo J, Schwarz PE, Sheu WHH, Snieder H, Spector TD, Tabara Y, Tuomilehto J, van Dam RM, Wilson JG, Wilson JF, Wolffenbuttel BHR, Wong TY, Wu JY, Yuan JM, Zonderman AB, Soranzo N, Guo X, Roberts DJ, Florez JC, Sladek R, Dupuis J, Morris AP, Tai ES, Selvin E, Rotter JI, Langenberg C, Barroso I, Meigs JB , Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis., PLoS Med. 2017;14(9):e1002383. DOI: 10.1371/journal.pmed.1002383

White LO, Ising M, von Klitzing K, Sierau S, Michel A, Klein AM, Andreas A, Keil J, Quintero L, Müller-Myhsok B, Uhr M, Gausche R, Manly JT, Crowley MJ, Kirschbaum C, Stalder T, Reduced hair cortisol after maltreatment mediates externalizing symptoms in middle childhood and adolescence., J Child Psychol Psychiatry. 2017, DOI: 10.1111/jcpp.12700

Wichmann G, Herchenhahn C, Boehm A, Mozet C, Hofer M, Fischer M, Kolb M, Dietz A, HLA traits linked to development of head and neck squamous cell carcinoma affect the progression-free survival of patients., Oral Oncol. 2017;69:115-127. DOI: 10.1016/j.oraloncology.2017.04.017

Windholz J, Kovacs P, Schlicke M, Franke C, Mahajan A, Morris AP, Lemke JR, Klammt J, Kiess W, Schöneberg T, Pfäffle R, Körner A, Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children., J Pediatr Endocrinol Metab. 2017;30(5):507-515. DOI: 10.1515/jpem-2016-0435

Yazbeck AM, Tout KR, Stadler PF, Hertel J, Towards a Consistent, Quantitative Evaluation of MicroRNA Evolution., J Integr Bioinform. 2017;14(1). pii: /j/jib.2017.14.issue-1/jib-2016-0013/jib-2016-0013.xml. DOI: 10.1515/jib-2016-0013

Yazbeck AM, Tout KR, Stadler PF, Detailed secondary structure models of invertebrate 7SK RNAs., RNA Biol. 2017:1-7. DOI: 10.1080/15476286.2017.1412913

Zeynalova N, Zeynalova S, Schimpf S, Hanisch F, Hinz A, Löffler M, Prävalenz von Angst bei Personen mit und ohne eine durchlebte Krebserkrankung, Gesundheitswesen 2017; 79(08/09): 656-804, DOI: 10.1055/s-0037-1606026

Zeynalova S, Kornej J, Loeffler M,  Tautenhahn S, Stoebe S, Engel C,  Thiery J, Wirkner K, Burkhardt R,  Baber R, Husser D, Hagendorff A; PR interval prolongation as intermediate phenotype for atrial fibrillation: Association with left atrial diameter, Troponin T und NT-proBNP (the LIFE-Adult-Study), European Heart Journal, 2017, 38 (1); ehx493.P5505, DOI: 10.1093/eurheartj/ehx493.P5505

Zeynalova S, Teren A, Henger S, Burkhardt R, Thiery J, Scholz M, Ergänzung des ARRIBA-Scores zur besseren Prädiktion der Mortalität (LIFE-Heart Studie), Gesundheitswesen 2017; 79(08/09): 656-804, DOI: 10.1055/s-0037-160598

Zeynalova S, Scholz M, Tautenhahn S, Wirkner K, Hagendorff A, Loeffler M, Sensitivität von NT-proBNP hinsichtlich Ausschluss einer Herzinsuffizienz, Gesundheitswesen 2017; 79(08/09): 656-804, DOI: 10.1055/s-0037-1605986

Zeller T, Seiffert M, Müller C, Scholz M, Schäffer A, Ojeda F, Drexel H, Mündlein A, Kleber ME, März W, Sinning C, Brunner FJ, Waldeyer C, Keller T, Saely CH, Sydow K, Thiery J, Teupser D, Blankenberg S, Schnabel R; Genome-Wide Association Analysis for Severity of Coronary Artery Disease Using the Gensini Scoring System., Front Cardiovasc Med. 2017;4:57. DOI: 10.3389/fcvm.2017.00057.

Zewinger S, Kleber ME, Tragante V, McCubrey RO, Schmidt AF, Direk K, Laufs U, Werner C, Koenig W, Rothenbacher D, Mons U, Breitling LP, Brenner H, Jennings RT, Petrakis I, Triem S, Klug M, Filips A, Blankenberg S, Waldeyer C, Sinning C, Schnabel RB, Lackner KJ, Vlachopoulou E, Nygård O, Svingen GFT, Pedersen ER, Tell GS, Sinisalo J, Nieminen MS, Laaksonen R, Trompet S, Smit RAJ, Sattar N, Jukema JW, Groesdonk HV, Delgado G, Stojakovic T, Pilbrow AP, Cameron VA, Richards AM, Doughty RN, Gong Y, Cooper-DeHoff R, Johnson J, Scholz M, Beutner F, Thiery J, Smith JG, Vilmundarson RO, McPherson R, Stewart AFR, Cresci S, Lenzini PA, Spertus JA, Olivieri O, Girelli D, Martinelli NI, Leiherer A, Saely CH, Drexel H, Mündlein A, Braund PS, Nelson CP, Samani NJ, Kofink D, Hoefer IE, Pasterkamp G, Quyyumi AA, Ko YA, Hartiala JA, Allayee H, Tang WHW, Hazen SL, Eriksson N, Held C, Hagström E, Wallentin L, Åkerblom A, Siegbahn A, Karp I, Labos C, Pilote L, Engert JC, Brophy JM, Thanassoulis G, Bogaty P, Szczeklik W, Kaczor M, Sanak M, Virani SS, Ballantyne CM, Lee VV, Boerwinkle E, Holmes MV, Horne BD, Hingorani A, Asselbergs FW, Patel RS; GENIUS-CHD consortium, Krämer BK, Scharnagl H, Fliser D, März W, Speer T, Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study., Lancet Diabetes Endocrinol. 2017, 5(7), 534-543, pii: S2213-8587(17)30096-7. DOI: 10.1016/S2213-8587(17)30096-7

Zülke AE, Kersting A, Dietrich S, Luck T, Riedel-Heller SG, Stengler K, [Screening Instruments for the Detection of Male-Specific Symptoms of Unipolar Depression - A Critical Overview]., Psychiatr Prax. 2017, 45(4):178-187, DOI: 10.1055/s-0043-120289

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