LIFE Forschungszentrum

Publikationen 2011

Beutner F, Teupser D, Gielen S, Holdt LM, Scholz M, Boudriot E, Schuler G, Thiery J
Rationale and Design of the Leipzig (LIFE) Heart Study: Phenotyping and Cardiovascular Patients with Coronary Artery Disease. PloS One 6(12) DOI: 10.1371/journal.pone.0029070

Binder H, Fasold M, Hopp L, Cakir V, von Bergen M, Wirth H
Molecular phenotypic portraits-exploring te "OMES" with Individual resolution. HIBIT conference proceedings

Bocsi J, Mittag A, Pierzchalski A, Osmancik P, Dähnert I, Tarnok A
Classification and discrimination of pediatric patients undergoing open heart surgery with and without methylprednisolone treatment by cytomics. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IX. SPIE DOI: 10.1117/12.876487

Böselt I, Tramma D, Kalamitsou S, Niemeyer T, Nykänen P, Gräf, K-J, Krude H, Marenzi KS, Di Candia S, Schöneberg T, Schulz A
Functional characterization of novel loss-of-function mutations in the vasopressin type 2 receptor gene causing nephrogenic diabetes insipidus. Nephrol Dial Transpl 0 DOI: 10.1093/ndt/gfr487

Buck D, Cepok S, Hoffmann S, Grummel V, Joachim A, Berthele A, Hartung H-P, Wassmuth R, Hemmer, B
Influence of the HLA-DRB1 Genotype on Antibody Development to Interferon Beta in Multiple Sclerosis.  Arch Neorol 68 (4) DOI: 10.1001/archneurol.2011.65

Burkhardt R, Breslow J L
TRIBI, chromosome 8 and the regulation of blood lipids. Clin Lipidol 6(2) DOI: 10.2217/CLP.11.5

Burkhardt R, Sündermann N, Ludwig D, Ceglarek U, Holdt LM, Thiery J, Teupser D
Cosegregation of Aortic Root Atherosclerosis and Intermediate Lipid Phenotypes on Chromosomes 2 and 8 in an Intercross of C57BL/6 and BALBc/ByJ Low-Density Lipoprotein Receptor -/- Mice. Arterioscler Thromb Vasc Biol 31 DOI: 10.1161/ATVBAHA.110.213843

Dukart J, Schroeter ML, Mueller K.,The Alzheimer's Diseases neuroimaging Initiative
Age Correction in Dementia – Matching to a Healthy Brain. Plos One 6(7) DOI: 10.1371/journal.pone.0022193

Ehreke L, Luck T, Luppa M, König HH, Villringer A, Riedel-Heller SG
Clock Drawing Test - screening utility for mild cognitive impairment according to different scoring systems: results of the Leipzig Longitudinal Study of the Aged (LEILA 75+). Int Psychogeriatr 23(10)DOI: 10.1017/S104161021100144X

Ehreke L, Luppa M, König HH, Villringer A, Riedel-Heller SG
Does the Clock Drawing Test Predict Dementia? Results of the Leipzig Longitudinal Study of the Aged (LEILA 75+). Dement Geriatr Cogn Disord 31 DOI: 10.1159/000323317

Eibisch M, Fuchs B, Schiller J, Süß R, Teuber K
Analysis of Phospholipid Mixtures from Biological Tissues by Matrix-Assisted Laser Desorption and Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS): A Laboratory Experiment. J Chem Educ 88(4) DOI: 10.1021/ed1004905

Engel KMY, Schrök K, Teupser D, Holdt LM, Tönjes A, Kern M, Dietrich K, Kovacs P, Krügel U, Scheidt HA, Schiller J, Huster D, Brockmann GA, Augustin M, 
Thiery J, Blüher M, Stumvoll M, Schöneberg T, Schulz A
Reduced food intake and body wheigt in mice deficent for the G protein-coupled receptor GPR82. PlosONE 6(12) DOI: 10.1371/journal.pone.0029400

Fasold M, Langenberger D, Binder H, Stadler PF, Hoffmann S
DARIO: A ncRNA detection and analysis tool for next-generation sequencing experiments. Nucl Acid Res 39 DOI:10.1093/nar/gkr357

Findeiss S, Langenberger D, Stadler PF, Hoffmann S
Traces of Post-Transcriptional RNA Modifications in Deep Sequencing Data. Biol Chem 392(4) DOI: 10.1515/BC.2011.043

Fuchs B, Süß R, Teuber K, Eibisch M, Schiller J
Lipid analysis by thin-layerchromatography —A review of the current state. J Chromatogr A 1218(19) DOI: 10.1016/j.chroma.2010.11.066

Gross A,Tonjes A, Kovacs P, Veeramah KR, Ahnert P, Roshyara NR, Gieger C, Rueckert IM, Loeffler M, Stoneking M, Wichmann HE, Novembre J, Stumvoll M, Scholz M
Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays. BMC Genet 12 DOI: 10.1186/1471-2156-12-67

Hiemisch A, Kiess W, Brähler E
Mental job strain in a university children's hospital-a study on stress experience and the resulting employee health. Klin Padiatr  233(4) DOI: 10.1055/s-0031-1271812

Hoffmann S
Computational Analysis of High Throughput Sequencing Data. Bioinformatics for Omics Data: Methods and Protocols, Methods in Molecular Biology 719 DOI: 10.1007/978-1-61779-027-0_9

Holland H, Mocker K, Ahnert P, Kirsten H, Hantmann H, Koschny R, Bauer M, Schober R, Scholz M, Meixensberger J, Krupp W
High resolution genomic profiling and classical cytogenetics in a group of benign and atypical meningiomas. Cancer Genet 204 DOI: 10.1016/j.cancergen.2011.10.007

Kiess W, Sergejev E, Körner A, Hebebrand J
Is it possible to treat obesity in children and adolescents? Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz  54 DOI: 10.1007/s00103-011-1265-6

Kirsten T, Gross A, Hartung M, Kolb L, Rahm E
GOMMA: A Component-based Infrastructure for managing and analyzing Life Science Ontologies and their Evolution.  J Biomed Semantics 2 DOI: 10.1186/2041-1480-2-6

Kirsten H, Wilcke A, Ligges C, Boltze J, Ahnert P. 
Association study of a functional genetic variant in KIAA0319 in German dyslexics.Psychiat Genet (Epub ahead of print) 2012 22(4):216-7

Langenberger D,  Bartschat S, Hertel J, Hoffmann S, Tafer H, Stadler PF
MicroRNA or Not MicroRNA? Lecture Notes in Computer Science 6832 DOI: 10.1007/978-3-642-22825-4_1

Langenberger D, Pundhir S, Ekstrøm CT, Stadler PF, Hoffmann S, Gorodkin J
deepBlockAlign: A tool for aligning RNA-seq profiles of read block patterns. Bioinformatics 28(1) DOI: 10.1093/bioinformatics/btr598

Luck T, Luppa M, Angermeyer CM, Villringer A, König HH, Riedel-Heller SG
Impact of impairment in instrumental activities of daily living and mild cognitive impairment on time to incident dementia: results of the leipzig longitudinal study of the aged. Psychol Med 41 DOI: 10.1017/S003329171000142X

Luppa M, Gentzsch K, Angermeyer MC, Weyerer S, König HH, Riedel-Heller SG
Geschlechtsspezifische Prädiktoren von Institutionalisierung im Alter – Ergebnisse der Leipziger Längsschnittstudie in der Altenbevölkerung (LEILA 75+). Psychiat Praxis 38(4) DOI: 10.1055/s-0030-1248496

Luppa M, Sikorski C, Luck T, Weyerer S, Villringer A, HH König, Riedel-Heller SG
Prevalence and risk factors of latest-life depression – Results of the Leipzig Longitudinal Study of the Aged (LEILA 75+). Int J Geriatr Psychiatry 27(3) DOI: 10.1002/gps.2718

Olbrich S, Sander C, Matschinger H, Mergel R, Trenner M, Schönknecht P, Hegerl U
Brain and body: Associations between EEG-vigilance and the autonomous nervous system during rest. J Psychophysiol 25(4) DOI: 10.1027/0269-8803/a000061

Otto C, Hoffmann S, Gorodkin J, Stadler PF
Fast local fragment chaining using sum-of-pair gap costs. Algorithms Mol Biol 6 DOI:  10.1186/1748-7188-6-4

Sacher J, Neumann J, Fünfstück Tillmann, Solimann A, Villringer A, Schroeter ML
Mapping the depressed brain: A meta-analysis of structural and functional alterations in major depressive disorder. J Affect Disord 2012: 140(2) DOI: 10.1016/j.jad.2011.08.001

Scholz M, Engert A, Franklin J, Josting A, Diehl V, Hasenclever D, Loeffler M
Impact of first- and second-line treatment for Hodgkin’s lymphoma on incidence of AML/MDS and NHL-experience of German Hodgkin’s Lymphoma Study Group analysed by a parametric model of carcinogenesis. Ann Oncol 22(3) DOI: 10.1093/annonc/mdq408

Scholz M, Kirsten H
Comparison of scoring methods for the detection of causal genes with or without rare variants. BMC Proceedings 5(9) DOI: 10.1186/1753-6561-5-S9-S49

Schonhoff P, Körner A, Kratzsch J, Pfäffle R, Kiess W
Long Term Clinical Management of Girls with Turner Syndrome at a Center of Pediatric Endocrinology Exp Clin Endocrinol Diabetes 119(69) DOI: 10.1055/s-0031-1277140

Schroeter ML, Neumann J
Combined imaging markers dissociate Alzheimer’s disease and frontotemporal lobar degeneration – an ALE meta‑analysis. Front Aging Neurosci 3(10) DOI: 10.3389/fnagi.2011.00010

Schroeter ML, Vogt B, Frisch S, Becker G, Barthel H, Mueller K, Villringer A, Sabri O
Executive deficits are related to the inferior frontal junction in early dementia. Brain 135 DOI: 10.1093/brain/awr311

Schroeter ML, Vogt B, Frisch S, Becker G, Seese A, Barthel H, Mueller K, Villringer A, Sabri O
Dissociating behavioral disorders in early dementia—An FDG-PET study. Psychiat Res  194 DOI: 10.1016/j.pscychresns.2011.06.009

Schuster S, Hechler C, Gebauer C, Kies W, Kratzsch J
Leptin in maternal serum and breast milk: association with infants' body weight gain in a longitudinal study over 6 months of lactation. Pediatrr Res 70(6) DOI: 10.1203/PDR.0b013e31823214ea

Teuber K, Schiller J, Jacob U, Lüpold S, Orledge JM, Blount JD, Royle NJ, Hoodless A, Müller K
MALDI-TOF mass spectrometry as a simple tool to determine the phospholipid/glycolipid composition of sperm - Pheasant spermatozoa as one selected example. Animal Reprod Science 123 DOI: 10.1016/j.anireprosci.2011.01.009


Uciteli A, Groß S, Kireyev S, Herre H, An ontologically founded architecture for information systems in clinical and epidemiological research, J of Biomed Sematics, 2011, DOI: 10.1186/2041-1480-2-S4-S1


Veeramah KR, Tönjes A, Kovacs P, Gross A, Wegmann D, Geary P, Gasperikova D, Klimes I, Scholz M, Novembre J, Stumvoll M
Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity. Eur J Hum Genet 19(9) DOI: 10.1038/ejhg.2011.65

Wilke A, Ligges C, Burkhardt J, Alexander M, Wolf Ch, Quente E, Ahnert P, Hoffmann P, Becker A, Müller-Myhsok B, Cichon S, Boltze J, Kirsten H
Imaging genetics of FOXP2 in dyslexia. Eur J Hum Genet 20(2) DOI: 10.1038/ejhg.2011.160

Wirth H, Loeffler M, von Bergen M, Binder H
Expression cartography of human tissues using self organizing maps. BMC Bioindformatics 12 DOI: 10.1186/1471-2105-12-306

Wu J, Teuber K, Eibisch M, Fuchs B, Schiller J
Chlorinated and brominated phospholipids are generated under the influence of the Fenton reagent - A MALDI-TOF MS study. Chem Phys Lipids 164(1) DOI: 10.1016/j.chemphyslip.2010.09.010

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