LIFE Forschungszentrum

Publikationen 2012

Becker S, Kortz L, Helmschrodt C, Thiery J, Ceglarek U
LC-MS-based metabolomics in the clinical laboratory. J Chromatogr B Analyt Technol Biomed Life Sci. 883-884 DOI: 10.1016/j.jchromb.2011.10.018

Beutner F, Brendel D, Teupser D, Sass K, Mueller M, Ceglarek U, Thiery J
Effect of everolimus on pre-existing atherosclerosis in LDL-receptor deficient mice. Atherosclerosis 222(2) DOI: 10.1016/j.atherosclerosis.2012.03.003

Beutner F, Teren A, Gielen S, Schuler G, Wirkner K, Tiller D, Loeffler M, Scholz M
Automated photoplethysmography-based determination of ankle-brachial index: a validation study against Doppler sonography. Clin Res Cardiol. 101(11) DOI: 10.1007/s00392-012-0471-z

Bis JC, Kavousin M, Franceschini N, Isaacs A, ….., Thiery J, Ziegler A, Lakatta EG, …….., Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common varaints associated with carotid intima media thickness and plaque, NetGenet 2012, DOI: 10.1038/ng.920.

Breitfeld J, Tönjes A, Böttcher Y, Schleinitz D, Wiele N, Marzi C, Brockhaus C, Rathmann W, Huth C, Grallert H, Illig T, Blüher M, Kovacs P, Stumvoll M 
Genetic Variation in the Vaspin Gene Affects Circulating Serum Vaspin Concentrations. Int J Obesity 37(6) DOI: 10.1038/ijo.2012.133

Buchwald UTeupser D, Kuehnel F, Grohmann J, Schmieder N, Beindorff N, Schlumbohm C, Fuhrmann H, Einspanier A
Prenatal stress programs lipid metabolism enhancing cardiovascular risk in the female F1, F2 and F3 generation in the primate model common marmoset (Callithrix jacchus). J Med Primatol 41 DOI: 10.1111/j.1600-0684.2012.00551.x

Burkhardt J, Kirsten H, Holland H, Krupp W, Ligges C, Quente E, Boltze J, Ahnert P, Wilcke A. 
Association of rs2069459 in the CDK5 gene with dyslexia in a German cohort. Psychiatr Genet 22 (6) DOI: 10.1097/YPG.0b013e328353aeae

Burkhardt J, Kirsten H, Wolfram G, Quente E, Ahnert P
Differential allelic expression of IL13 and CSF2 genes associated with asthma. Genet Mol Biol 35(3) DOI: 10.1590/S1415-47572012005000055

Doehnert M, Brandeis D, Schneider G, Drechsler R, Steinhausen HC
A neurophysiological marker of impaired preparation in an 11-year follow-up study of attention-deficit/hyperactivity disorder (ADHD). J Child Psychol Psychiatry 54(3) DOI: 10.1111/j.1469-7610.2012.02572.x

Doose G, Metzler D
Bayesian sampling of evolutionarily conserved RNA secondary structures with pseudoknots. Bioinformatics 28(17) DOI: 10.1093/bioinformatics/bts369

Fasold M, Binder H. 
Estimating RNA-quality unsing Genechip microarrays. BMC Genomics 13(186) DOI: 10.1186/1471-2164-13-186

Fischer J, Böhm S, Scholz M, Müller T, Witt H, George J, Sarrazin C, Susser S, Schott E, Suppiah V, Booth D, Stewart G, van Bömmel F, Brodzinski A, Fülöp B, Migaud P, Berg T
Combined effects of different IL28B gene variants on the outcome of dual combination therapy in chronic HCV type 1 infection Hepatology. 55(6) DOI: 10.1002/hep.25582

Glauche I, Horn K, Horn M, Thielecke L, Essers MA, Trumpp A, Roeder I
Therapy of chronic myeloid leukaemia can benefit from the activation of stem cells: simulation studies of different treatment combinations. Brit J Cancer 106(11) DOI: 10.1038/bjc.2012.142

Gross A, Ziepert M, Scholz M
KMWin - A Convenient Tool for Graphical Presentation of Results from Kaplan-Meier Survival Time Analysis. PlosONE 6(7) DOI: 10.1371/journal.pone.0038960

Hegerl U, Hensch T. 
The vigilance regulation model of affective disorders and ADHA. Neurosci Biobehav 44 DOI: 10.1016/j.neubiorev.2012.10.008

Hertel J, Bartschat S, Wintsche A, Otto C, Of The Bioinformatics Computer Lab TS, Stadler PF
Evolution of the let-7 microRNA Family.  RNA Biol 9(3) DOI: 10.4161/rna.18974

Holdt LM, Teupser D 
Recent studies of the human chromosome 9p21 locus, which is associated with atherosclerosis in human populations. Arterioscler Thromb Vasc Biol 32 DOI: 10.1161/ATVBAHA.111.232678

Holiga S, Möller HE, Sieger T, Schroeter M, Jech R, Mueller K
Accounting for movement increases sensitivity in detecting brain activity in Parkinson's disease. PlosONE 7 (5) DOI: 10.1371/journal.pone.0036271

Holland H, Ahnert P, Koschny R, Kirsten H, Bauer M, Schober R, Meixensberger J, Fritzsch D, Krupp W
Detection of novel genomic aberrations in anaplastic astrocytomas by GTG-banding, SKY, locus-specific FISH, and high density SNP-array. Pathol Res Pract 208(6) DOI: 10.1016/j.prp.2012.03.010

Kirsten H, Wilcke A, Ligges C, Boltze J, Ahnert P. Association study of a functional genetic variant in KIAA0319 in German dyslexics.Psychiat Genet (Epub ahead of print ahead of print) 2012 22(4):216-7, DOI: 10.1097/YPG.0b013e32834c0c97

Kühnel F, Buchwald U, Grohmann J, Teupser D, Einspanier A
Parameters of haematology, clinical chemistry and lipid metabolism in the common marmoset and alterations under stress conditions. J Med Primatol 4(41) DOI: 10.1111/j.1600-0684.2012.00550.x

Luck T, Luppa M, Riedel-Heller SG
Epidemiology of dementia – A current overview. Public Health Forum 76 DOI: 10.1016/j.phf.2012.06.018

Luck T, Luppa M, Sieber J, Schomerus G, Werner P, König HH, Riedel-Heller SG
Attitudes of the German general population toward early diagnosis of dementia – Results of a representative telephone survey. PLoS ONE 7(11) DOI: 10.1371/journal.pone.0050792

Luck T, Luppa M, Wiese B, Maier W, van den Bussche H, Eisele M, Jessen F, Weeg D, Weyerer S, Pentzek M, Leicht H, Koehler M, Tebarth F, Olbrich J, Eifflaender-Gorfer S, Fuchs A, Koenig HH, Riedel-Heller SG
Prediction of Incident Dementia: Impact of Impairment in Instrumental Activities of Daily Living and Mild Cognitive Impairment – Results from the German Study on Ageing, Cognition and Dementia in Primary Care Patients. Am J Geriatr Psychiatry 20(11) DOI: 10.1097/JGP.0b013e31825c09bc

Luppa M, Luck T, König HH, Angermeyer MC, Riedel-Heller SG
Natural course of depressive symptoms in late life. An 8-year population-based prospective study. J Affect Disord 142(1-3) DOI: 10.1016/j.jad.2012.05.009

Luppa M, Sikorski C, Luck T, Weyerer S, Villringer A, König HH, Riedel-Heller SG
Prevalence and risk factors of depressive symptoms in latest life--results of the Leipzig Longitudinal Study of the Aged (LEILA 75+). Int J Geriatr Psychiatry. 27(3) DOI: 10.1002/gps.2718

Melchior C, Schulz A, Windholz J, Kiess W, Schöneberg T, Körner A., Clinical and functional relevance of melanocortin-4 receptor variants in obese German children., HormResPaediatr. 2012, DOI:10.1159/000343816

Milic I, Federova M, Teuber I, Schiller J, Hoffmann R
Characterization of oxidation products 1-palmitoyl-2-linoleoyl-sn-glycerophosphatidylcholine in aqueous solutions Q2 and their reactions with cysteine, histidine and lysine Q3 residues. Chem Phys Lipids 165(2) DOI: 10.1016/j.chemphyslip.2011

Mueller K, Sacher J, Arelin K, Holiga S, Kratzsch J, Villringer A, Schroeter ML 
Overweight & obesity are associated with neuronal injury in the human cerebellum & hippocampus in young adults: A combined MRI, serum marker and gene expression study. Translational Psychiatry 2 DOI: 10.1038/tp.2012.121

Mukherjee C, Koch E, Banusch J, Scholz M, Kaisers UX, Ender J 
Intrathecal morphine is superior to intravenous PCA in patients undergoing minimally invasive cardiac surgery. Ann Card Anaesth 15(2) DOI: 10.4103/0971-9784.95075

Mütze U, Beblo S, Kortz L, Glaser C, Brügel M, Rohde C, Thiery J, Kiess W, Ceglarek U
Metabolomics of Dietary Fatty Acid Restriction in Patients with Phenlyketonuria. PlosONE 7(8) DOI: 10.1371/journal.pone.0043021

Olbrich S, Sander C, Minkwitz J, Chittka T, Mergl R, Hegerl U, Himmerich H
EEG Vigilance Regulation Patterns and Their Discriminative Power to Separate Patients with Major Depression from Healthy Controls. Neuropsychobiology 65 DOI: 10.1159/000337000

Otto C, Reiche K, Hackermüller J. 
Detection of differentially expressed segments in tiling array data.  Bioinformatics  28 (11) DOI: 10.1093/bioinformatics/bts142

Otto C, Stadler FP, Hoffmann S. 
Fast and sensitive mapping of bisulfite-treated sequencing data. Bioinformatics 28 (13) DOI: 10.1093/bioinformatics/bts254

Quante M, Hesse M, Döhnert M, Fuchs M, Hirsch C, Sergeyev E, Casprzig N, Geserick M, naumann s, Koch C, Sabin MA, Hiemisch A, Körner A, Kiess W
The LIFE child study: a life course approach to disease and health. BMC Public Health 12(1) DOI: 10.1186/1471-2458-12-1021

Quinque EM, Arelin K, Dukart J, Roggenhofer E, Streitbürger DP, Villringer A, Frisch S, Mueller K, Schroeter ML
Identifying the neural correlates of executive functions in early cerebral microangiopathy: a combined VBM and DTI study. J Cerebr Blood F Met 32(10) DOI: 10.1038/jcbfm.2012.96

Richter J, Schlesner M, Hoffmann S, Kreuz M, Leich E, Burkhardt B, Rosolowski M, Ammerpohl O, Wagener R, Bernhart SH, Lenze D, Szczepanowski M, Paulsen M, Lipinski S, Russell RB, Adam-Klages S, Apic G, Claviez A, Hasenclever D, Hovestadt V, Hornig N, Korbel JO, Kube D, Langenberger D, Lawerenz C, Lisfeld J, Meyer K, Picelli S, Pischimarov J, Radlwimmer B, Rausch T, Rohde M, Schilhabel M, Scholtysik R, Spang R, Trautmann H, Zenz T, Borkhardt A, Drexler HG, Möller P, MacLeod RA, Pott C, Schreiber S, Trümper L, Loeffler M, Stadler PF, Lichter P, Eils R, Küppers R, Hummel M, Klapper W, Rosenstiel P, Rosenwald A, Brors B, Siebert R; ICGC MMML-Seq Project
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing. Nat Genet 44(12) DOI: 10.1038/ng.2469

Richter M, Bishop CA, Dukart J, Stuehler E, Mueller K, Schroeter ML, Merhof D
Skeleton-based gyri sulci separation for improved assessment of cortical thickness. IEEE-ISBI conference proceedings DOI: 10.1109/ISBI.2012.6235762/ Print ISBN:978-1-4577-1857-1

Ritscher L, Engemaier E, Stäubert C, Liebscher I, Schmidt P, Hermsdorf T, Römpler H, Schulz A, Schöneberg T
The ligand specificity of the G-protein-coupled receptor GPR34. Biochem J. 443(3) DOI: 10.1042/BJ20112090
Rohlf T, Steiner L, Przybilla J, Prohaska S, Binder H, Galle J
Modeling the dynamic epigenome: from histone modifications towards self-organizing chromatin. Epigenomics 4(2) DOI: 10.2217/epi.11.117

Rohlf T, Steiner L, Przybilla J, Prohaska S, Binder H, Galle J. Modeling the dynamic epigenome: from histone modifications towards self-organizing chromatin. Epigenomics  2012, 4(2): 205-219, DOI: 10.2217/epi.11.117

Roling G, Sesselmann Y, Fleischer S, Beutner K, Behrens J, Luck T, Luppa M, Riedel-Heller SG
Handlungsanleitung für die Durchführung Präventiver Hausbesuche. Hallesche Beiträge zu den Gesundheits- und Pflegewissenschaften 11 (2)

Saalbach A, Vester K, Rall K, Tremel J, Anderegg U, Beck-Sickinger AG, Blüher M, Simon JC
Vaspin - a link of obisity and psoriasis. Exp Dermatol 21(4) DOI: 10.1111/j.1600-0625.2012.01460.x.

Schmidtke C, Findeiß S, Sharma CM, Kuhfuß J, Hoffmann S, Vogel J, Stadler PF, Bona U
Genome-wide transcriptome analysis of the plant pathogen Xanthomonas identifies sRNAs with putative virulence functions. Nucl Acid Res 40(5) DOI: 10.1093/nar/gkr904

Scholz M, Schirm S, Wetzler M, Engel C, Loeffler M
Pharmacokinetic and -dynamic modelling of G-CSF derivatives in humans. Theor Biol Med Model 9(32) DOI: 10.1186/1742-4682-9-32

Schroeter ML
Considering the frontomedian cortex in revised criteria for behavioural variant frontotemporal dementia. Brain 135 DOI: 10.1093/brain/aws030

Steiner L, Hopp L, Wirth H, Galle J, Binder H, Prohaska S J , Rohlf T
A Global Genome Segmentation Method for Exploration of Epigenetic Patterns. PlosONE 7(10) DOI: 10.1371/journal.pone.0046811

Streitbürger DP, Arelin K, Kratzsch J, Thiery J, Steiner J, Villringer A, Mueller K, Schroeter M
Validating serum S100B and neuron-specific enolase as biomarkers for the human brain- a combined serum, gene expression and MRI study. PlosONE 7(8) DOI:  10.1371/journal.pone.0043284

Teuber K, Federova M, Teuber I, Hoffmann R, Schiller J
2,4-Dinitrophenylhydrazine as a new reactive matrix to analyze oxidized phospholipids by MALDI-TOF mass spectrometry. Anal Lett 45 DOI: 10.1080/00032719.2012.670785

Wirth H, von Bergen M, Binder H
Mining SOM expression portraits: Feature selection and integrating concepts of molecular function. BioData Min 5 (1) DOI: 10.1186/1756-0381-5-18

Wirth H, v Bergen M, Murugaiyan J, Rösler U, Stokowsky T, Binder H
MALDI-typing of infectious algae of the genus Prototheca using SOM portraits. J Microbiol Meth 88(1) DOI: 10.1016/j.mimet.2011.10.013

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