LIFE Health Study

Publikationen 2016

Annibal A, Riemer T, Jovanovic O, Westphal D, Griesser E, Pohl EE, Schiller J, Hoffmann R, Fedorova M, Structural, biological and biophysical properties of glycated and glycoxidized phosphatidylethanolamines, Free Radic Biol Med. 2016, pii: S0891-5849(16)00117-9. DOI: 10.1016/j.freeradbiomed.2016.03.011

Barth C, Steele CJ, Mueller K, Rekkas VP, Arélin K, Pampel A, Burmann I, Kratzsch J, Villringer A, Sacher J, In-vivo Dynamics of the Human Hippocampus across the Menstrual Cycle., Sci Rep. 2016; 6:32833. DOI: 10.1038/srep32833.

Berg M, Fuchs M, Wirkner K, Loeffler M, Engel C, Berger T, The Speaking Voice in the General Population: Normative Data and Associations to Sociodemographic and Lifestyle Factors., J Voice. 2016, pii: S0892-1997(16)30055-8. DOI: 10.1016/j.jvoice.2016.06.001

Bernhart SH, Kretzmer H, Holdt LM, Jühling F, Ammerpohl O, Bergmann AK, Northoff BH, Doose G, Siebert R, Stadler PF, Hoffmann S, Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer., Sci Rep. 2016; 6:37393. DOI: 10.1038/srep37393.

Bisenius S, Neumann JSchroeter ML, Response to the letter on 'Validating new diagnostic imaging criteria for primary progressive aphasia via anatomical likelihood estimation meta-analyses'., Eur J Neurol. 2016, 23(8):e52-3. DOI: 10.1111/ene.13046.

Bisenius S, Neumann J, Schroeter ML, Validating new diagnostic imaging criteria for primary progressive aphasia via anatomical estimation meta-analyses, Europea Journal of Neurology, 2016, DOI: 10.1111/ene.12902.

Brauer J, Xiao Y, Poulain T, Friederici AD, Schirmer A, Frequency of Maternal Touch Predicts Resting Activity and Connectivity of the Developing Social Brain, Cereb Cortex. 2016, DOI:10.1093/ceror/bhw13.

Bremer S, Kiess W, Thome U, Knüpfer M, Bühligen U, Vogel M, Friedrich A, Janisch U, Rißmann A, Prevalence of Gastroschisis, Omphalocele, Spina Bifida and Orofacial Clefts of Neonates from January 2000 to December 2010 in Leipzig, Saxony, Saxony-Anhalt and Germany, Gesundheitswesen 2016, DOI: 10.1055/s-0042-102345

Canzler S,  Stadler FP, Hertel J, U6 snRNA Intron Insertion Occurred Multiple Times During Fungi Evolution., RNA Biol. 2016, DOI: 10.1080/15476286.2015.1132139

Canzler S,  Stadler FP, Hertel J, U6 snRNA Intron Insertion Occurred Multiple Times During Fungi Evolution., RNA Biol. 2016, DOI: 10.1080/15476286.2015.1132139.

Ceglarek U, Kresse K, Becker S, Fiedler GM, Thiery J, Quante M, Wieland R, Bartels M, Aust G, Circulating sterols as predictors of early allograft dysfunction and clinical outcome in patients undergoing liver transplantation., Metabolomics. 2016;12(12):182. Epub 2016, DOI: 10.1007/s11306-016-1129-z

Dathan-Stumpf A, Vogel M, Hiemisch A, Thiery J, Burkhardt R, Kratzsch J, Kiess W, Pediatric reference data of serum lipids and prevalence of dyslipidemia: Results from a population-based cohort in Germany, Clinical Biochemistry 2016, DOI: 10.1016/j.clinbiochem.2016.02.010

Dathan-Stumpf A, Vogel M, Rieger K, Thiery J, Hiemisch A, Kiess W, Serum lipid levels were related to socio-demographic characteristics in a German population-based child cohort.Acta Paediatr. 2016 Apr 20. DOI: 10.1111/apa.13438.

Daxer J, Herttrich T, Zhao YY, Vogel MHiemisch A, Scheuermann K, Körner A, Kratzsch J, Kiess W, Quante M,  Nocturnal levels of chemerin and progranulin in adolescents: influence of sex, body mass index, glucose metabolism and sleep.,  J Pediatr Endocrinol Metab. 2016. pii: /j/jpem.ahead-of-print/jpem-2016-0378/jpem-2016-0378.xml.,  DOI: 10.1515/jpem-2016-0378.

Doose G, Hoffmann S, Iaccarino I, Reply to Hart et al.: MINCR and MYC: More than expression correlation., Proc Natl Acad Sci U S A., 2016, pii: 201520413, DOI: 10.1073/pnas.1520413113.

Dorow J, Becker S, Kortz L, Thiery J, Hauschildt S, Ceglarek U, Preanalytical Investigation of Polyunsaturated Fatty Acids and Eicosanoids in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry., Biopreserv Biobank. , 2016, DOI:10.1089/bio.2015.0005.

García-García I, Kube J, Gaebler M, Horstmann A, Villringer A, Neumann J., Neural processing of negative emotional stimuli and the influence of age, sex and and task-related characteristics., Neurosci Biobehav Rev. , 2016, pii: S0149-7634(15)30202-5. DOI:10.1016/j.neubiorev.2016.04.020.

Gaudl A, Kratzsch JBae YJKiess WThiery JCeglarek U, Liquid chromatography quadrupole linear ion trap mass spectrometry for quantitative steroid hormone analysis in plasma, urine, saliva and hair., J Chromatogr A. 2016, 1464: 64-71, pii: S0021-9673(16)31028-7., DOI: 10.1016/j.chroma.2016.07.087.

Günther V, Rufer M, Kersting A, Suslow T. Predicting symptoms in major depression after inpatient treatment: the role of alexithymia, Nord J Psychiatry. 2016, DOI: 10.3109/08039488.2016.1146796

Hamdi Y, ... Engel C, ...., Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3., Breast Cancer Res Treat. 2016, DOI: 10.1007/s10549-016-4018-2.

Hamidouche Z, Rother K, Przybilla J, Krinner A, Clay D, Hopp L, Fabian C, Stolzing A, Binder H, Charbord P, Galle J., Bistable epigenetic states explain age-dependent decline in mesenchymal stem cell heterogeneity., Stem Cells. 2016, DOI: 10.1002/stem.2514.

Hezaveh K, Kloetgen A, Bernhart SH, ..., Hoffmann S, ..., Kretzmer H, ..., Stadler PF, ...; ICGC MMML-Seq Project., Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis., Haematologica. 2016, 101(11):1380-1389, DOI:10.3324/haematol.2016.143891

Hinz A, Klein AM, Brähler E, Glaesmer H, Luck T, Riedel-Heller SG, Wirkner K, Hilbert A, Psychometric evaluation of the Generalized Anxiety Disorder Screener GAD-7, based on a large German general population sample., J Affect Disord. 2016;210:338-344. DOI: 10.1016/j.jad.2016.12.012.

Holdt LM, Stahringer A, Sass K, Pichler G, Kulak NA, Wilfert W, Kohlmaier A, Herbst A, Northoff BH, Nicolaou A, Gäbel G, Beutner F, Scholz M, Thiery J, Musunuru K, Krohn K, Mann M, Teupser D, Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans., Nat Commun. 2016, 7:12429. DOI: 10.1038/ncomms12429.

Hölzer M, Krähling V, Amman F, Barth E, Bernhart SH, Carmelo VA, Collatz M, Doose G, Eggenhofer F, Ewald J, Fallmann J, Feldhahn LM, Fricke M, Gebauer J, Gruber AJ, Hufsky F, Indrischek H, Kanton S, Linde J, Mostajo N, Ochsenreiter R, Riege K, Rivarola-Duarte L, Sahyoun AH, Saunders SJ, Seemann SE, Tanzer A, Vogel B, Wehner S, Wolfinger MT, Backofen R, Gorodkin J, Grosse I, Hofacker I, Hoffmann S, Kaleta C, Stadler PF, Becker S, Marz M., Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells., Sci Rep. 2016;6:34589. DOI: 10.1038/srep34589.

Hörnig F, Kohajda T, Röder S, Herberth G, von Bergen M, Borte M, Diez U, Rolle-Kampczyk U, Simon JC, Denburg JA, Lehmann I, Junge KM, The LINA Study: Higher Sensitivity of Infant Compared to Maternal Eosinophil/Basophil Progenitors to Indoor Chemical Exposures, J of Environmental and Public Health, 2016, DOI: org/10.1155/2016/5293932.

Jawinski P, Mauche N, Ulke C, Huang J, Spada J, Enzenbach C, Sander C, Hegerl U, Hensch T, Tobacco use is associated with reduced amplitude and intensity dependence of the cortical auditory evoked N1-P2 component., Psychopharmacology (Berl). 2016; DOI: 10.10077S00213-016-4268-Z

Jawinski P, Tegelkamp S, Sander C, Häntzsch M, Huang J, Mauche N, Scholz M, Spada J, Ulke C, Burkhardt R, Reif A, Hegerl U, Hensch T, Time to wake up: No impact of COMT Val158Met gene variation on circadian preferences, arousal regulation and sleep. Chronobiol Int. 2016 May 5:1-13. DOI:10.1080/07420528.2016.1178275

Kassa TA, Luck T, Bekele A, Riedel-Heller SG, Sexual and reproductive health of young people with disability in Ethiopia: a study on knowledge, attitude and practice: a cross-sectional study, Global Health., 2016, Doi: 10.1186/s12992-016-0142-3

Keil J, Michel A, Sticca  F, Leipold K, Klein AM, Sierau S, von Klitzing K, White LO, The Pizzagame: A virtual public goods game to assess cooperative behavior in children and adolescents. Behavior research methods, 2016, DOI:10.3758/s13428-016-0799-9.

Khamis H, Shimoni S, Hagendorff A, Smirin N, Friedman Z, Adam D., Optimization Based Speckle Tracking Algorithm for Left Ventricle Strain Estimation: a Feasibility Study., IEEE Trans Ultrason Ferroelectr Freq Control. 2016, DOI:10.1109/TUFFC.2016.2569619,IEEE, [Epub ahead of print]

Kharabian Masouleh S, Arélin K, Horstmann A, Lampe L, Kipping JA, Luck T, Riedel-Heller SG, Schroeter ML, Stumvoll M, Villringer A, Witte AV, Higher body mass index in older adults is associated with lower gray matter volume: implications for memory performance, Neurobiology of Aging, 2016, DOI: 10.1016/j.neurobiolaging.2015.12.020

Kinny-Köster B, Bartels M, Becker S, Scholz M, Thiery J, Ceglarek U, Kaiser T, Plasma Amino Acid Concentrations Predict Mortality in Patients with End-Stage Liver DiseasePLoS One. 2016; 11(7):e0159205. DOI: 10.1371/journal.pone.0159205. eCollection 2016.

Kirsten T, Bumberg J, Ivanova G, Dietrich P, Engel C, Loeffler M, Kiess W, On Integrating Health and Environmental Data in Epidemiological Studies, Kongressbeitrag INCLUDE Workshop, 2016 

Kraft I, Schreiber J, Cafiero R, Metere R, Schaadt G, Brauer J, Neef NE, Müller B, Kirsten H, Wilcke A, Boltze J, Friederici AD, Skeide MA, Predicting early signs of dyslexia at a preliterate age by combining behavioral assessment with structural MRI., Neuroimage. 2016, pii: S1053-8119(16)30465-7. DOI: 10.1016/j.neuroimage.2016.09.004.

Kuehnapfel A, Ahnert P, Loeffler M, Broda A, Scholz M, Reliability of 3D laser-based anthropometry and comparison with classical anthropometry., Sci Rep., 2016; 6:26672. DOI: 10.1038/srep26672.

Landgraf K, Scholz M, Kovacs P, Kiess W, Körner A, FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children - Relevance of FTO Variants to Defend Body Weight in Lean Children?, PLoS One. 2016;11(8):e0161739. DOI:10.1371/journal.pone.0161739. eCollection 2016.

Lange HVogel M, Ohlendorf A, Wahl S, Wiedemann P, Kiess W, Rauscher FG, Prevalence of refractive errors in a large German cohort of children and adolescents, ARVO Annual Meeting Abstract, 2016, Vol.57(12), 3974

Liem F, Varoquaux G, Kynast J, Beyer F, Masouleh SK, Huntenburg JM, Lampe L, Rahim M, Abraham A, Craddock RC, Riedel-Heller S, Luck T, Loeffler M, Schroeter ML, Witte AV, Margulies DS; Predicting brain-age from multimodal imaging data captures cognitive impairment., Neuroimage. 2016, pii: S1053-8119(16)30610-3. DOI: 10.1016/j.neuroimage.2016.11.005.

Lin YC, Groß A, Kirsten T: Integration and Visualization of Spatial Data in LIFE. Proc. Intl. Conf. of Data Integration in the Life Sciences, 2016.

Löffler-Wirth H, Willscher E, Ahnert P, Wirkner K, Engel C, Loeffler M, Binder H, Novel Anthropometry Based on 3D-Bodyscans Applied to a Large Population Based Cohort., PLoS One. 2016;11(7):e0159887. DOI: 10.1371/journal.pone.0159887.

Loley C, ..., Scholz M, ..., Beutner F, ..., Thiery J, ... , No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis., Sci Rep. 2016; 6:35278. DOI: 10.1038/srep35278

Luck T, Then FS, Engel C, Löffler M, Thiery J, Villringer A, Riedel-Heller SG, The Prevelance of Current Depressive Symptoms in an Urban Adult Population, Results of the Leipzig Population-Based Study of Adults (LIFE-ADULT-Study), PsychiatPrax 2016, DOI: 10.1055/s-0041-111428 Psychiat Prax 2016

Müller B, Wilcke A, Boulesteix AL, Brauer J, Passarge E, Boltze J, Kirsten H, Improved prediction of complex diseases by common genetic markers: State of the art and further perspectives, Hum Gent, 2016, DOI: 10.1007/s00439-016-1635-z.

Müller B, Wilcke A, Czepezauer I, Ahnert P, Boltze J, Kirsten H, LEGASCREEN consortium, Association, characterisation and meta-analysis of SNPs linked to general reading ability in a German dyslexia case-control cohort, Sci Rep., 2016, 6:27901. DOI: 10.1038/srep27901.

Mueller K, Arelin K, Möller HE, Sacher J, Kratzsch J, Luck T, Riedel-Heller S, Villringer A, Schroeter ML, Serum BDNF correlates with connectivity in the (pre)motor hub in the aging human brain – a resting-state fMRI pilot study, Neurobiology of Aging, 2016, DOI:10.1016/j.neurobiolaging.2015.11.003

Ohlendorf A, Lange H, Vogel M,  Wahl S, Wiedemann P, Kiess W, Rauscher FG, Prevalence of myopia and astigmatism in adults in Germany, ARVO Annual Meeting Abstract, 2016, Vol.57(12), 3979

Rieger K, Vogel M, Engel C, Ceglarek U, Thiery J, Kratzsch J, Harms K, Glock F, Hiemisch A, Kiess W, Reference intervals for iron-related blood parameters: results from a population-based cohort study (LIFE Child), J Lab Med 2016, DOI: 10.1515/labmed-2015-0093

Roehr S, Luck T, Heser K, Fuchs A, Ernst A, Wiese B, Werle J, Bickel H, Brettschneider C, Koppara A, Pentzek M, Lange L, Prokein J, Weyerer S, Mösch E, König HH, Maier W, Scherer M, Jessen F, Riedel-Heller SG, AgeCoDe Study Group, Incident Subjective Cognitive Decline  Does Not Predict Mortality in the Elderly – Results from the Longitudinal German Study on Ageing, Cognition, and Dementia (AgeCoDe), PlosOne, 2016, DOI: 10.1371/journal.pone.0147050

Roehr S, Villringer A, Angermeyer MC, Luck TRiedel-Heller SG, Outcomes of stable and unstable patterns of subjective cognitive decline - results from the Leipzig Longitudinal Study of the Aged (LEILA75+)., BMC Geriatr. 2016;16(1):180.; DOI: 10.1186/s12877-016-0353-8

Roshyara NR, Horn K, Kirsten H, Ahnert P, Scholz M, Comparing performance of modern genotype imputation methods in different ethnicities., Sci Rep. 2016;6:34386. DOI: 10.1038/srep34386

Sander C, Hegerl U, Wirkner K, Walter N, Kocalevent RD, Petrowski K, Glaesmer H, Hinz A, Normative values of the Epworth Sleepiness Scale (ESS), derived from a large German sample., Sleep Breath 2016, DOI: 10.1007/s11325-016-1363-7.

Scherag A, Schöneweck F, Kesselmeier M, Taudien S, Platzer M, Felder M, Sponholz C, Rautanen A, Hill AV, Hinds CJ, Hossain H, Suttorp N, Kurzai O, Slevogt H, Giamarellos-Bourboulis EJ, Armaganidis A, Trips E, Scholz M, Brunkhorst FM, Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality., EBioMedicine. 2016, pii: S2352-3964(16)30399-1. DOI: 10.1016/j.ebiom.2016.08.043.

Schirm S, Ahnert P, Wienhold, Mueller-Redetzky H, Nouailles-Kursar G, Loeffler M, Witzenrath M, Scholz M, A Biomathematical Model of Pneumococcal Lung Infection and Antibiotic Treatment in Mice, PLoS One. 2016;11(5):e0156047. DOI: 10.1371/journal.pone.0156047.

Schmidt R, Richter R, Brauhardt A, Hiemisch A, Kiess W, Hilbert A, Parental feeding practices in families with children aged 2-13 years: Psychometric properties and child age-specific norms of the German version of the Child Feeding Questionnaire (CFQ)., Appetite. 2016;109:154-164. DOI: 10.1016/j.appet.2016.11.038.

Schreier M, Schwartze JT, Landgraf K, Scheuermann K,  Erbs S, Herberth G, Pospisilik JA, Kratzsch J, Kiess WKörner A, Osteopontin is BMI-independently Related to Early Endothelial Dysfunction in Children., J Clin Endocrinol Metab. 2016;101(11):4161-4169, DOI: 10.1210/jc.2016-2238

Schrimpf A, Kube J, Neumann J, Horstmann A, Villringer AGaebler M, Parasympathetic cardio-regulation during social interactions in individuals with obesity-The influence of negative body image., Cogn Affect Behav Neurosci. 2016, DOI: 10.3758/s13415-016-0482-8

Schümberg K, Polyakova M, Steiner J, Schroeter ML, Serum S100B Is Related to Illness Duration and Clinical Symptoms in Schizophrenia-A Meta-Regression Analysis, Front Cell Neurosci. 2016, DOI: 10.3389/fncel.2016.00046. eCollection 2016

Skeide MA, Kraft I, Müller B, Schaadt G, Neef NE, Brauer J, Wilcke A, Kirsten H, Boltze J, Friederici AD, NRSN1 associated grey matter volume of the visual word form area reveals dyslexia before school., Brain. 2016,  139(Pt 10):2792-2803., DOI: 10.1093/brain/aww153

Sonnengrün L, Schober C, Vogel M, Hiemisch A, Döhnert M, Hilbert A, Kiess W., Feeding, eating and behavioral disturbances in Prader-Willi syndrome and non-syndromal obesity., J Pediatr Endocrinol Metab. 2016, pii: /j/jpem.ahead-of-print/jpem-2016-0085/jpem-2016-0085.xml. DOI: 10.1515/jpem-2016-0085

Spada J, Scholz M, Kirsten H, Hensch T, Horn K, Jawinski P, Ulke C, Burkhardt R, Wirkner K, Loeffler M, Hegerl U, Sander C, Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study. J Sleep Res. 2016, DOI: 10.1111/jsr.12421.

Stadelmann S, Grunewald M, Gibbels C, Jaeger S, Matuschek T, Weis S, Klein AM, Hiemisch A, von Klitzing K, Döhnert M, Self-Esteem of 8-14-Year-Old Children with Psychiatric Disorders: Disorder- and Gender-Specific Effects, Child Psychiatry Hum Dev., 2016, DOI 10.1007/s10578-016-0651-6 

Stadler SC, Hacker U, Burkhardt R, Cholesterol metabolism and breast cancer, Curr Opin Lipidol. 2016 Apr;27(2):200-1. DOI: 10.1097/MOL.0000000000000285.

Teren A, Beutner F, Wirkner K, Löffler M, Scholz M, Relationship Between Determinants of Arterial Stiffness Assessed by Diastolic and Suprasystolic Pulse Oscillometry: Comparison of Vicorder and Vascular Explorer., Medicine (Baltimore). 2016 Mar;95(10):e2963. DOI: 10.1097/MD.0000000000002963. 

Then FS, Luck T, Angermeyer MC, Riedel-Heller SG, Education as protector against dementia, but what exactly do we mean by education?, Age Ageing. 2016 Apr 7. pii: afw049; DOI:10.1093/ageing/afw049

Then FS, Luck T, Heser K, Ernst A, Posselt T, Wiese B, Mamone S, Brettschneider C, König HH, Weyerer S, Werle J, Mösch E, Bickel H, Fuchs A, Pentzek M, Maier W, Scherer M, Wagner M, Riedel-Heller SG; AgeCoDe Study Group, Which types of mental work demands may be associated with reduced risk of dementia?, Alzheimers Dement. 2016, pii: S1552-5260(16)32888-6. DOI: 10.1016/j.jalz.2016.08.008

Then FS, Schroeter ML, Witte V, Engel C, Löffler M, Thiery J, Villringer A, Luck T, Riedel-Heller SG, The Cognitive Functioning of Socially Isolated Individuals may Profit from High Mental Work Demands, Gesundheitswesen 2016; 78 - A60, DOI: 10.1055/s-0036-1586570

Treudler R, Walther F, Ahnert P, Simon JC, Adverse drug reactions in elderly people : First data from the Leipzig Research Center for Civilization Diseases (LIFE), Hautarzt. 2016, DOI:10.1007/s00105-016-3897-9.

Ulke C, Sander C, Jawinski P, Mauche N, Huang J, Spada J, Wittekind D, Mergl R, Luck TRiedel-Heller SHensch T, Hegerl U., "Sleep disturbances and upregulation of brain arousal during daytime in depressed versus non-depressed elderly subjects"., World J Biol Psychiatry. 2016:1-21., DOI: 10.1080/15622975.2016.1224924.

Vausort M, Salgado-Somoza A, Zhang L, Leszek P, Scholz M, Teren A, Burkhardt R, Thiery J, Wagner DR, Devaux Y., Myocardial Infarction-Associated Circular RNA Predicting Left Ventricular Dysfunction., J Am Coll Cardiol. 2016;68(11):1247-8. DOI: 10.1016/j.jacc.2016.06.040.

Volovitz I, Melzer S, Amar S, Bocsi J, Bloch M, Efroni S, Ram Z, Tárnok A, Dendritic Cells in the Context of Human Tumors: Biology and Experimental Tools, Int Rev Immunol. 2016, 35(2):116-35. DOI: 10.3109/08830185.2015.1096935

Wolfsgruber S, Kleineidam L, Wagner M, Mösch E, Bickel H, Lϋhmann D, Ernst A, Wiese B, Steinmann S, König HH, Brettschneider C, Luck T, Stein J, Weyerer S, Werle J, Pentzek M, Fuchs A, Maier W, Scherer M, Riedel-Heller SG, Jessen F; AgeCoDe Study Group, Differential Risk of Incident Alzheimer's Disease Dementia in Stable Versus Unstable Patterns of Subjective Cognitive Decline., J Alzheimers Dis. 2016, DOI: 10.3233/JAD-160407.

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